1-bromo-4-nitro-2-phenylmethoxy-benzene

Base Information

• Chemical Name: 1-bromo-4-nitro-2-phenylmethoxy-benzene
• CAS No.: 6345-68-2
• Molecular Formula: C13H10 Br N O3
• Molecular Weight: 308.131
• Hs Code.: 2909309090
• Mol file: 6345-68-2.mol

Synonyms:3-Benzyloxy-4-bromonitrobenzene;NSC 43575

Chemical Property of 1-bromo-4-nitro-2-phenylmethoxy-benzene

Chemical Property:

• Vapor Pressure: 9.65E-07mmHg at 25°C
• Melting Point: 111.5-112.5 °C
• Boiling Point: 415.8°C at 760 mmHg
• Flash Point: 205.3°C
• PSA: 55.05000
• Density: 1.524g/cm³
• LogP: 4.45950

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-bromo-4-nitro-2-phenylmethoxy-benzene

There total 3 articles about 1-bromo-4-nitro-2-phenylmethoxy-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

1-bromo-2-fluoro-4-nitrobenzene (185331-69-5) + benzyl alcohol (100-51-6,185532-71-2) → 2-(benzyloxy)-1-bromo-4-nitrobenzene (6345-68-2)

Guidance literature:

benzyl alcohol; With sodium hydride; In tetrahydrofuran; mineral oil; at 20 ℃; for 0.166667h;

1-bromo-2-fluoro-4-nitrobenzene; In tetrahydrofuran; mineral oil; at 20 ℃; for 2h;

Reference yield:

2-bromo-5-nitrophenol (52427-05-1) + benzyl bromide (100-39-0) → 2-(benzyloxy)-1-bromo-4-nitrobenzene (6345-68-2)

Guidance literature:

2-bromo-5-nitrophenol; With potassium carbonate; In ethanol; at 90 ℃; for 2h;

benzyl bromide; With potassium iodide; In ethanol;

DOI:10.1016/j.ejmech.2015.04.013

Reference yield:

2-bromo-5-nitrophenol (52427-05-1) + benzyl chloride (100-44-7) → 2-(benzyloxy)-1-bromo-4-nitrobenzene (6345-68-2)

Guidance literature:

With potassium carbonate; acetone;

DOI:10.1021/ja01164a028

upstream raw materials:

2-bromo-5-nitrophenol

benzyl chloride

benzyl bromide

1-bromo-2-fluoro-4-nitrobenzene

Downstream raw materials:

3-(benzyloxy)-4-bromoaniline

bis-(2-benzyloxy-4-nitro-phenyl)-sulfone

bis-(2-benzyloxy-4-nitro-phenyl)-sulfide