Stlpn

Base Information

Chemical Name:Stlpn
CAS No.:99242-09-8
Molecular Formula:C34H39 N5 O9
Molecular Weight:661.712
Hs Code.:
DSSTox Substance ID:DTXSID10912822
Mol file:99242-09-8.mol

Synonyms:STLPN;Suc-Tyr-Leu-Phe-pNA;succinyl-tyrosyl-leucyl-phenylalanine-4-nitroanilide

Suppliers and Price of Stlpn

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Stlpn

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:233.5 - 235 °C (ethyl acetate)
Boiling Point:1074.9°Cat760mmHg
Flash Point:603.9°C
PSA：219.75000
Density:1.325g/cm³
LogP:4.85850
XLogP3:3.7
Hydrogen Bond Donor Count:6
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:16
Exact Mass:661.27477784
Heavy Atom Count:48
Complexity:1090

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCC(C)C(C(=O)NC(CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)C(CC3=CC=C(C=C3)O)NC(=O)CCC(=O)O
Isomeric SMILES:CCC(C)[C@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)[C@H](CC3=CC=C(C=C3)O)NC(=O)CCC(=O)O

Technology Process of Stlpn

There total 9 articles about Stlpn which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 108-30-5
succinic acid anhydride

: 776253-75-9
H-L-Tyr-D-Leu-D-Phe-pNA

: 99242-09-8
Suc-L-Tyr-D-Leu-D-Phe-pNA

Guidance literature:: With sodium carbonate; triethylamine; In water; ethyl acetate; Ambient temperature;
DOI:10.1248/cpb.33.5301

Reference yield:

: 2448-45-5
Cbz-D-Phe

: 99242-09-8
Suc-L-Tyr-D-Leu-D-Phe-pNA

Guidance literature:: Multi-step reaction with 7 steps

1: 35 percent

2: 25percent HBr, acetic acid

3: 84 percent / 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide, Et₃N / dimethylformamide / Ambient temperature

4: 5N HCl / dioxane

5: 58 percent / 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide, Et₃N / dimethylformamide / Ambient temperature

6: 5N HCl / dioxane

7: 61 percent / Na₂CO₃, Et₃N / H₂O; ethyl acetate / Ambient temperature

With hydrogenchloride; hydrogen bromide; sodium carbonate; benzotriazol-1-ol; acetic acid; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.33.5301

Reference yield:

: 16937-99-8,53296-34-7
N-Boc-D-Leu

: 99242-09-8
Suc-L-Tyr-D-Leu-D-Phe-pNA

Guidance literature:: Multi-step reaction with 5 steps

1: 84 percent / 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide, Et₃N / dimethylformamide / Ambient temperature

2: 5N HCl / dioxane

3: 58 percent / 1-hydroxybenzotriazole, N,N'-dicyclohexylcarbodiimide, Et₃N / dimethylformamide / Ambient temperature

4: 5N HCl / dioxane

5: 61 percent / Na₂CO₃, Et₃N / H₂O; ethyl acetate / Ambient temperature

With hydrogenchloride; sodium carbonate; benzotriazol-1-ol; triethylamine; dicyclohexyl-carbodiimide; In 1,4-dioxane; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1248/cpb.33.5301