1,2-Dihydro-1-tosylquinoline

Base Information

• Chemical Name: 1,2-Dihydro-1-tosylquinoline
• CAS No.: 13268-54-7
• Molecular Formula: C16H15NO2S
• Molecular Weight: 285.367
• Hs Code.: 2935009090
• Mol file: 13268-54-7.mol

Synonyms:1-tosyl-1,2-dihydroquinoline;1,2-dihydro-1-tosylquinoline;1,2-Dihydro-1-p-tosyl-chinolin;

Chemical Property of 1,2-Dihydro-1-tosylquinoline

Chemical Property:

• Vapor Pressure: 4.84E-08mmHg at 25°C
• Boiling Point: 442.9°Cat760mmHg
• Flash Point: 221.7°C
• PSA: 45.76000
• Density: 1.273g/cm³
• LogP: 4.36290

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,2-Dihydro-1-tosylquinoline

There total 25 articles about 1,2-Dihydro-1-tosylquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(7E,15E)-5,13-ditosyl-5,6,13,14-tetrahydrodibenzo[b,h][1,7]diazacyclododecine (1038502-69-0) → 1-tosyl-1, 2-dihydroquinoline (13268-54-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; -butyl vinyl ether; In toluene; Inert atmosphere; Heating;

DOI:10.1016/j.tet.2009.04.071

Reference yield: 94.0%

1,2,3,4-tetrahydro-4-hydroxy-1-tosylquinoline (24206-42-6) → 1-tosyl-1, 2-dihydroquinoline (13268-54-7)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 2h; Heating;

Reference yield: 93.0%

N-allyl-4-methyl-N-(2-vinyl-phenyl)-benzenesulfonamide (497066-36-1) → 1-tosyl-1, 2-dihydroquinoline (13268-54-7)

Guidance literature:

tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; In dichloromethane; at 50 ℃; for 1h;

DOI:10.1002/anie.200290031

upstream raw materials:

1,2-dihydroquinoline

p-toluenesulfonyl chloride

1,2,3,4-tetrahydro-4-hydroxy-1-tosylquinoline

N-tosyl-o-allylaniline

Downstream raw materials:

quinoline

3-phenylquinoline

1,2,3,4-tetrahydro-3-(2'-hydroxyphenyl)quinoline

7,12-dihydro-7-tosyl-6,12-methano-2,3-methylenedioxy-6H-dibenzo<1,3>oxazocine