2-[4-(2-amino-4-thiazolyl)phenoxy]Acetic acid

Base Information

Chemical Name:2-[4-(2-amino-4-thiazolyl)phenoxy]Acetic acid
CAS No.:168127-34-2
Molecular Formula:C₁₁H₁₀N₂O₃S
Molecular Weight:250.278
Hs Code.:2934100090
DSSTox Substance ID:DTXSID80168495
Wikidata:Q83038102
Mol file:168127-34-2.mol

Synonyms:168127-34-2;2-[4-(2-amino-4-thiazolyl)phenoxy]Acetic acid;2-(4-(2-aminothiazol-4-yl)phenoxy)acetic acid;2-[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid;(4-(2-Amino-4-thiazolyl)phenoxy)acetic acid;Acetic acid, (4-(2-amino-4-thiazolyl)phenoxy)-;Acetic acid, [4-(2-amino-4-thiazolyl)phenoxy]-;MFCD01751282;[4-(2-amino-1,3-thiazol-4-yl)phenoxy]acetic acid;2-{4-(2-Amino-4-thiazolyl)phenoxy}acetic acid;2-(4-(2-amino-1,3-thiazol-4-yl)phenoxy)acetic acid;2-[4-(2-Amino-4-thiazolyl)phenoxy]aceticAcid;AMY436;SCHEMBL7473221;DTXSID80168495;HYDGPYDSIOCNTN-UHFFFAOYSA-N;BBL029462;STL146730;AKOS005720982;AS-32179;SY012613;CS-0448043;FT-0738324;Acetic acid, 2-[4-(2-amino-4-thiazolyl)phenoxy]-

Suppliers and Price of 2-[4-(2-amino-4-thiazolyl)phenoxy]Acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-[4-(2-Amino-4-thiazolyl)phenoxy]aceticAcid
100mg
$ 60.00

Crysdot
2-(4-(2-Aminothiazol-4-yl)phenoxy)aceticacid 95+%
5g
$ 314.00

Chemenu
2-(4-(2-Aminothiazol-4-yl)phenoxy)aceticacid 95%
5g
$ 294.00

American Custom Chemicals Corporation
2-[4-(2-AMINO-4-THIAZOLYL)PHENOXY]ACETIC ACID 95.00%
5MG
$ 496.64

Alichem
2-(4-(2-Aminothiazol-4-yl)phenoxy)aceticacid
5g
$ 590.58

Alichem
2-(4-(2-Aminothiazol-4-yl)phenoxy)aceticacid
1g
$ 191.07

AK Scientific
2-[4-(2-Amino-4-thiazolyl)phenoxy]aceticacid
1g
$ 215.00

Total 11 raw suppliers

Chemical Property of 2-[4-(2-amino-4-thiazolyl)phenoxy]Acetic acid

Chemical Property:

Vapor Pressure:2.38E-11mmHg at 25°C
Boiling Point:513°Cat760mmHg
Flash Point:264.1°C
PSA：114.41000
Density:1.431g/cm³
LogP:1.78580
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:250.04121336
Heavy Atom Count:17
Complexity:269

Purity/Quality:

97% ^*data from raw suppliers

2-[4-(2-Amino-4-thiazolyl)phenoxy]aceticAcid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=CSC(=N2)N)OCC(=O)O

Technology Process of 2-[4-(2-amino-4-thiazolyl)phenoxy]Acetic acid

There total 6 articles about 2-[4-(2-amino-4-thiazolyl)phenoxy]Acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 168127-29-5
[4-(2-Amino-thiazol-4-yl)-phenoxy]-acetic acid ethyl ester

: 168127-34-2
2-(4-(2-aminothiazol-4-yl)phenoxy)acetic acid

Guidance literature:: With sulfuric acid; for 3h; Heating;

Reference yield: 61.2%

: 1878-81-5
4-acetylphenoxyacetic acid

: 17356-08-0
thiourea

: 168127-34-2
2-(4-(2-aminothiazol-4-yl)phenoxy)acetic acid

Guidance literature:: With iodine; In N,N-dimethyl-formamide; for 18h; Heating;
DOI:10.1016/j.ejmech.2010.03.043

Reference yield:

: 51828-69-4
ethyl (4-acetylphenoxy)-acetate

: 168127-34-2
2-(4-(2-aminothiazol-4-yl)phenoxy)acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: 84 percent / acetonitrile / 3 h / Heating

2: ethanol / 6 h / Heating

3: 64 percent / 20percent H₂SO₄ / 3 h / Heating

With sulfuric acid; In ethanol; acetonitrile;