ethyl (4-acetylphenoxy)acetate

Base Information

• Chemical Name: ethyl (4-acetylphenoxy)acetate
• CAS No.: 51828-69-4
• Molecular Formula: C12H14 O4
• Molecular Weight: 222.241
• Mol file: 51828-69-4.mol

Synonyms:Aceticacid, (4-acetylphenoxy)-, ethyl ester (9CI); Ethyl (4-acetylphenoxy)acetate;Ethyl p-acetylphenoxyacetate; [4-(Acetyl)phenoxy]acetic acid ethyl ester

Chemical Property of ethyl (4-acetylphenoxy)acetate

Chemical Property:

• Vapor Pressure: 7.18E-05mmHg at 25°C
• Boiling Point: 343.1°C at 760 mmHg
• Flash Point: 151.2°C
• Density: 1.122g/cm³

Purity/Quality:

98%Min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ethyl (4-acetylphenoxy)acetate

There total 5 articles about ethyl (4-acetylphenoxy)acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

ethyl bromoacetate (105-36-2) + 4-Hydroxyacetophenone (99-93-4) → ethyl (4-acetylphenoxy)-acetate (51828-69-4)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 18h;

Reference yield: 95.0%

chloroacetic acid ethyl ester (105-39-5) + 4-Hydroxyacetophenone (99-93-4) → ethyl (4-acetylphenoxy)-acetate (51828-69-4)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 18h;

DOI:10.1016/j.bmc.2010.12.023

Reference yield: 80.0%

ethyl 4-(bromoacetyl)phenoxyacetate (29936-82-1) → ethyl (4-acetylphenoxy)-acetate (51828-69-4)

Guidance literature:

With water; 1-methyl-3-pentyl-1H-imidazolium tetrafluoroborate; at 125 ℃; for 0.075h; under 2585.74 Torr; microwave irradiation;

DOI:10.1016/j.tet.2006.10.035

upstream raw materials:

ethyl 4-(bromoacetyl)phenoxyacetate

chloroacetic acid ethyl ester

4-Hydroxyacetophenone

ethyl bromoacetate

Downstream raw materials:

N,N-Diethyl-N'-<(4-acetyl-phenoxy)-acetyl>-ethylendiamin

2-(4-Acetyl-phenoxy)-N-[2-(2-hydroxy-2-phenyl-ethylamino)-ethyl]-acetamide

ethyl 4-(2-tosyloxyacetyl)phenoxyacetate

ethyl 4-(bromoacetyl)phenoxyacetate