4-DiMethylaMino-2,2-diphenylvaleric Acid

Base Information

• Chemical Name: 4-DiMethylaMino-2,2-diphenylvaleric Acid
• CAS No.: 5348-94-7
• Molecular Formula: C19H23 N O2
• Molecular Weight: 297.397
• Mol file: 5348-94-7.mol

Synonyms:Valeric acid, 4-dimethylamino-2,2-diphenyl- (6CI);4-Dimethylamino-2,2-diphenylpentanoic acid; 4-Dimethylamino-2,2-diphenylvalericacid; NSC 1361

Chemical Property of 4-DiMethylaMino-2,2-diphenylvaleric Acid

Chemical Property:

• Vapor Pressure: 3.52E-06mmHg at 25°C
• Boiling Point: 371.6°Cat760mmHg
• Flash Point: 178.5°C
• PSA: 40.54000
• Density: 1.097g/cm³
• LogP: 3.39750

Purity/Quality:

99% ^*data from raw suppliers

4-Dimethylamino-2,2-diphenyl valeric acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methadone metabolite.

Technology Process of 4-DiMethylaMino-2,2-diphenylvaleric Acid

There total 5 articles about 4-DiMethylaMino-2,2-diphenylvaleric Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(R,S)-2,2-diphenyl-4-dimethylaminopentanenitrile (125-79-1) → (+/-)-4-Dimethylamino-2,2-diphenylpentanoic acid (5348-94-7) + aminopentamide (60-46-8,5985-87-5,5985-88-6,6078-64-4)

Guidance literature:

With sulfuric acid;

DOI:10.1039/jr9490000648

Reference yield:

(R,S)-2,2-diphenyl-4-dimethylaminopentanenitrile (125-79-1) → (+/-)-4-Dimethylamino-2,2-diphenylpentanoic acid (5348-94-7)

Guidance literature:

With sulfuric acid;

DOI:10.1021/ja01169a016 DOI:10.1039/jr9490000648 DOI:10.1021/ja01189a022

Reference yield:

(R)-(-)-2,2-diphenyl-4-dimethylaminopentanenitrile (7576-16-1) → (R)-4-dimethylamino-2,2-diphenyl-valeric acid (5348-94-7)

Guidance literature:

With sulfuric acid;

upstream raw materials:

(R,S)-2,2-diphenyl-4-dimethylaminopentanenitrile

(R)-(-)-2,2-diphenyl-4-dimethylaminopentanenitrile

Downstream raw materials:

recipavrin

4-dimethylamino-2,2-diphenyl-pentan-1-ol

(+/-)-1,5-dimethyl-3,3-diphenyl-2-pyrrolidone