CHEMBRDG-BB 4022458

Base Information

• Chemical Name: CHEMBRDG-BB 4022458
• CAS No.: 4438-01-1
• Molecular Formula: C11H15NO2
• Molecular Weight: 193.246
• Hs Code.: 2934999090
• Mol file: 4438-01-1.mol

Synonyms:2-N-Morpholinomethyl-phenol;2-morpholinomethylphenol;2-morpholin-4-ylmethylphenol;

Chemical Property of CHEMBRDG-BB 4022458

Chemical Property:

• Vapor Pressure: 0.000416mmHg at 25°C
• Boiling Point: 306.8°Cat760mmHg
• Flash Point: 139.4°C
• PSA: 32.70000
• Density: 1.169g/cm³
• LogP: 1.16230

Purity/Quality:

95% ^*data from raw suppliers

2-(morpholin-4-ylmethyl)phenol 95% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xn
• Statements: 22-41

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of CHEMBRDG-BB 4022458

There total 16 articles about CHEMBRDG-BB 4022458 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

morpholine (110-91-8,99108-56-2) + o-dimethylaminomethylphenol methylammonium iodide (26753-12-8) → 2-(morpholinomethyl)phenol (4438-01-1)

Guidance literature:

With sodium hydroxide; at 80 ℃; for 1h; pH=12;

DOI:10.1021/jo0006627

Reference yield: 98.5%

morpholine (110-91-8,99108-56-2) + phenylboronic acid (98-80-6) → 2-(morpholinomethyl)phenol (4438-01-1)

Guidance literature:

With di-tert-butyl peroxide; In dichloromethane; at 80 ℃; for 10h; Temperature; Reagent/catalyst;

Reference yield: 94.0%

morpholine (110-91-8,99108-56-2) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + phenylboronic acid (98-80-6) → 2-(morpholinomethyl)phenol (4438-01-1)

Guidance literature:

With tert.-butylhydroperoxide; In dichloromethane; water; at 80 ℃; for 8h; Concentration; Reagent/catalyst; Solvent; Temperature; regioselective reaction; Sealed tube;

DOI:10.1016/j.tetlet.2017.02.081

upstream raw materials:

morpholine

formaldehyd

phenol

2-(1H-1,2,3-benzotriazol-1-ylmethyl)phenol

Downstream raw materials:

o-acetoxybenzyl acetate

(2,4,6-Trimethyl-phenyl)-carbamic acid 2-morpholin-4-ylmethyl-phenyl ester

(2-Hexyloxy-phenyl)-carbamic acid 2-morpholin-4-ylmethyl-phenyl ester

(2-Octyloxy-phenyl)-carbamic acid 2-morpholin-4-ylmethyl-phenyl ester