3-CHLORO-3-METHYLBUTANONE

Base Information

• Chemical Name: 3-CHLORO-3-METHYLBUTANONE
• CAS No.: 5950-19-6
• Molecular Formula: C5H9 Cl O
• Molecular Weight: 120.579
• Mol file: 5950-19-6.mol

Synonyms:3-Chloro-3-methyl-2-butanone;3-Methyl-3-chloro-2-butanone; NSC 167067

Chemical Property of 3-CHLORO-3-METHYLBUTANONE

Chemical Property:

• Vapor Pressure: 2.55E-15mmHg at 25°C
• Refractive Index: 1.42004 (20℃)
• Boiling Point: 601.5°C at 760 mmHg
• Flash Point: 317.6°C
• PSA: 17.07000
• Density: 1.44g/cm³
• LogP: 1.59280

Purity/Quality:

99% ^*data from raw suppliers

3-CHLORO-3-METHYLBUTANONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-CHLORO-3-METHYLBUTANONE

There total 3 articles about 3-CHLORO-3-METHYLBUTANONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-methyl-butan-2-one (563-80-4) → 1-chloro-3-methylbutan-2-one (17687-63-7) + 3-chloro-3-methyl-2-butanone (5950-19-6)

Guidance literature:

With chlorine; In methanol; Product distribution; 1.) 20-50 deg C, 2.) room temperature, 0.5 h; other solvent;

DOI:10.1021/jo00325a019

Reference yield:

3-methyl-butan-2-one (563-80-4) + chlorine (7782-50-5) → 1,3-Dichloro-3-methyl-2-butanone (57539-84-1) + 1-chloro-3-methylbutan-2-one (17687-63-7) + 3-chloro-3-methyl-2-butanone (5950-19-6)

Guidance literature:

at 95 - 100 ℃;

Reference yield:

3-Hydroxy-3-methyl-2-butanone (115-22-0) + 1-chloro-1-(dimethylamino)-2-methyl-1-propene (26189-59-3) → 3-Methyl-3-buten-2-one (814-78-8,25988-32-3) + 3-chloro-3-methyl-2-butanone (5950-19-6) + C11H22NO2(1+)*Cl(1-)

Guidance literature:

In dichloromethane; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.tet.2015.11.060

upstream raw materials:

3-methyl-butan-2-one

chlorine

3-Hydroxy-3-methyl-2-butanone

1-chloro-1-(dimethylamino)-2-methyl-1-propene

Downstream raw materials:

Trimethylacetic acid

3-methyl-3-phenoxy-butan-2-one oxime

3-Hydroxy-3-methyl-2-butanone

3-(4-clorofenossi)-3-metilbutanone