trimethylsilyl 4-isothiocyanatobutanoate

Base Information

• Chemical Name: trimethylsilyl 4-isothiocyanatobutanoate
• CAS No.: 28733-15-5
• Molecular Formula: C₈H₁₅NO₂SSi
• Molecular Weight: 217.364
• Mol file: 28733-15-5.mol

Synonyms:Butyricacid, 4-isothiocyanato-, trimethylsilyl ester (8CI); Silanol, trimethyl-,4-isothiocyanatobutyrate (8CI); 4-Isothiocyanatobutyric acid trimethylsilylester; NSC 218447

Chemical Property of trimethylsilyl 4-isothiocyanatobutanoate

Chemical Property:

• Vapor Pressure: 0.0182mmHg at 25°C
• Boiling Point: 253.5°Cat760mmHg
• Flash Point: 107.1°C
• Density: 1.01g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of trimethylsilyl 4-isothiocyanatobutanoate

There total 2 articles about trimethylsilyl 4-isothiocyanatobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-trimethyl-silane (75-77-4) + 4-Ethylsulfanylthiocarbonylamino-butyric acid → 4-Isothiocyanatobuttersaeure-trimethylsilyester (28733-15-5)

Guidance literature:

With triethylamine;

Reference yield:

chloro-trimethyl-silane (75-77-4) + thiophosgene (463-71-8) + 4-amino-n-butyric acid (56-12-2) → 4-Isothiocyanatobuttersaeure-trimethylsilyester (28733-15-5)

Guidance literature:

Multistep reaction; (i) CHCl₃, THF, (ii) /BRN= 1633495/, Et₃N;

upstream raw materials:

chloro-trimethyl-silane

thiophosgene

4-amino-n-butyric acid