Norscopolamine

Base Information

Chemical Name:Norscopolamine
CAS No.:4684-28-0
Molecular Formula:C16H19NO4
Molecular Weight:289.331
Hs Code.:2933991200
European Community (EC) Number:225-139-6
Nikkaji Number:J297.886E
Wikipedia:Norscopolamine
Mol file:4684-28-0.mol

Synonyms:(S)-norscopolamine;norscopolamine

Suppliers and Price of Norscopolamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
NorScopolamine
5mg
$ 185.00

Sigma-Aldrich
Hyoscine impurity A European Pharmacopoeia (EP) Reference Standard
y0000484
$ 198.00

Sigma-Aldrich
Hyoscine hydrobromide impurity B European Pharmacopoeia (EP) Reference Standard
y0000448
$ 190.00

Medical Isotopes, Inc.
NorScopolamine
50 mg
$ 2200.00

Arctom
Norscopolamine ≥98%
5mg
$ 513.00

Total 23 raw suppliers

Chemical Property of Norscopolamine

Chemical Property:

Boiling Point:474.7°Cat760mmHg
PKA:14.11±0.10(Predicted)
Flash Point:240.9°C
PSA：71.09000
Density:1.34g/cm³
LogP:0.90470
XLogP3:0.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:289.13140809
Heavy Atom Count:21
Complexity:393

Purity/Quality:

HPLC≥98% ^*data from raw suppliers

NorScopolamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(CC2C3C(C1N2)O3)OC(=O)C(CO)C4=CC=CC=C4
Isomeric SMILES:C1[C@@H]2[C@@H]3[C@@H](O3)[C@@H](N2)CC1OC(=O)C(CO)C4=CC=CC=C4
Uses Scopolamine (S200000) metabolite.

Technology Process of Norscopolamine

There total 10 articles about Norscopolamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 51-34-3,138-12-5,64069-63-2,124917-17-5
scopolamine

: 4684-28-0
Norscopolamine

Guidance literature:: With sodium perchlorate; water; for 3h; Electrochemical reaction; Green chemistry;
DOI:10.1039/d0gc00851f

Reference yield:

: 114-49-8
hyoscine hydrobromide

: 4684-28-0
Norscopolamine

Guidance literature:: With potassium permanganate; potassium carbonate;
DOI:10.1002/jlac.19697290119

Reference yield:

: 6820-79-7
9-methyl-3-oxa-9-azatricyclo[3.3.1.0(2,4)]non-7-yl-3'-(acetyloxy)-2'-phenyl propanoate

: 4684-28-0
Norscopolamine

Guidance literature:: Multi-step reaction with 3 steps

1: 81.2 percent / toluene / 1.) 5 h, RT; 2.) 4 d, RT

2: H₂O / 1 h / 93 °C

3: 1.) 36percent HCl; 2.) NaOH / 1.) H₂O, 2 h, RT; 2.) H₂O, 10 deg C to 15 deg C

With hydrogenchloride; sodium hydroxide; water; In toluene;