oxonan-2-one

Base Information

• Chemical Name: oxonan-2-one
• CAS No.: 5698-29-3
• Molecular Formula: C8H14 O2
• Molecular Weight: 142.198
• Mol file: 5698-29-3.mol

Synonyms:Octanoicacid, 8-hydroxy-, lactone (6CI); Octanoic acid, 8-hydroxy-, h-lactone (7CI); 8-Octanolactone;8-Octanolide; Oxacyclononan-2-one; h-Caprylolactone; w-Hydroxyoctanoic acid lactone

Chemical Property of oxonan-2-one

Chemical Property:

• Vapor Pressure: 0.0239mmHg at 25°C
• Boiling Point: 248.7°Cat760mmHg
• Flash Point: 96.7°C
• PSA: 26.30000
• Density: 0.965g/cm³
• LogP: 1.88380

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of oxonan-2-one

There total 1 articles about oxonan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Cyclooctan (292-64-8) → oxonan-2-one (5698-29-3) + cycloactanone (502-49-8) + cyclooctanol (696-71-9)

Guidance literature:

With D-glucose; alcohol dehyrogenase TeSADH; Baeyer–Villiger monooxygenase; cyclohexanone monooxygenase_M₁₆; cytochrome P₄₅₀ BM₃ monooxygenase; formate dehydrogenase CboFDH; sodium formate; NADP; In glycerol; at 30 ℃; for 24h; pH=8; Catalytic behavior; Enzymatic reaction;

DOI:10.1002/cctc.201402835

Reference yield: 94.0%

oxonan-2-one (5698-29-3) + chloromethyl phenyl sulfoxide (7205-94-9) → 1-benzenesulfinyl-1-chloro-9-hydroxy-nonan-2-one

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1016/S0040-4039(98)02101-7

Reference yield: 71.0%

oxonan-2-one (5698-29-3) + aniline (62-53-3) → 8-hydroxy-N-phenyloctanamide

Guidance literature:

With 1,3,4,6,7,8-hexahydro-2H-pyrimido[1,2-a]pyrimidine; at 100 ℃; for 24h;

DOI:10.1002/cssc.201700415

upstream raw materials:

Cyclooctan

Downstream raw materials:

3-Keto-10-hydroxy-decansaeure-nitril

1,8-Octanediol

octanol

(E)-10-hydroxy-dec-2-enoic acid

Refernces

• 1、 Pennec, Aliz,Hollmann, Frank,Smit, Martha S.,Opperman, Diederik J.. "One-pot conversion of cycloalkanes to lactones". . p. 236 - 239. Retrieved 2015/03/04.