N-[(4-Methylphenyl)methyl]-2-(morpholin-4-yl)-5-(piperidine-1-sulfonyl)benzamide

Base Information

• Chemical Name: N-[(4-Methylphenyl)methyl]-2-(morpholin-4-yl)-5-(piperidine-1-sulfonyl)benzamide
• CAS No.: 5711-07-9
• Molecular Formula: C24H31N3O4S
• Molecular Weight: 253.993
• DSSTox Substance ID: DTXSID20368992
• Wikidata: Q82155931
• ChEMBL ID: CHEMBL1479170
• Mol file: 5711-07-9.mol

Synonyms:5711-07-9;N-[(4-methylphenyl)methyl]-2-morpholin-4-yl-5-piperidin-1-ylsulfonylbenzamide;N-[(4-Methylphenyl)methyl]-2-(morpholin-4-yl)-5-(piperidine-1-sulfonyl)benzamide;MLS002170370;CHEMBL1479170;DTXSID20368992;HMS3046M24;AKOS034050443;SMR001250687;Z28428301

Chemical Property of N-[(4-Methylphenyl)methyl]-2-(morpholin-4-yl)-5-(piperidine-1-sulfonyl)benzamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.252g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 457.20352765
• Heavy Atom Count: 32
• Complexity: 705

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N3CCCCC3)N4CCOCC4

Technology Process of N-[(4-Methylphenyl)methyl]-2-(morpholin-4-yl)-5-(piperidine-1-sulfonyl)benzamide

There total 3 articles about N-[(4-Methylphenyl)methyl]-2-(morpholin-4-yl)-5-(piperidine-1-sulfonyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

silver(I) acetate (563-63-3) + indole-2,3-dione (91-56-5,1186480-61-4,84788-92-1) → indoline-2,3-dione; silver (I)-compound (5711-07-9)

Guidance literature:

In not given;

DOI:10.1021/jo01035a033

Reference yield:

isatin sodium salt (3486-31-5) + silver nitrate → indoline-2,3-dione; silver (I)-compound (5711-07-9)

Guidance literature:

In water; fine distributed Na-salt of ligand;

DOI:10.1021/jo01035a033

Reference yield:

→ indoline-2,3-dione; silver (I)-compound (5711-07-9)

Guidance literature:

Isatin, Silbercarbonat;

DOI:10.1021/jo00889a028

upstream raw materials:

silver(I) acetate

indole-2,3-dione

isatin sodium salt

Downstream raw materials:

silver(l) oxide