alpha-(4-Methylphenyl)-2-benzofuranmethanol

Base Information

Chemical Name:alpha-(4-Methylphenyl)-2-benzofuranmethanol
CAS No.:82158-21-2
Molecular Formula:C16H14O2
Molecular Weight:238.2812
Hs Code.:
DSSTox Substance ID:DTXSID001002508

Synonyms:alpha-(4-Methylphenyl)-2-benzofuranmethanol;2-Benzofuranmethanol, alpha-(4-methylphenyl)-;82158-21-2;SCHEMBL10537724;DTXSID001002508;AKOS012391928;LS-35198;(1-Benzofuran-2-yl)(4-methylphenyl)methanol

Suppliers and Price of alpha-(4-Methylphenyl)-2-benzofuranmethanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of alpha-(4-Methylphenyl)-2-benzofuranmethanol

Chemical Property:

Vapor Pressure:6.93E-07mmHg at 25°C
Boiling Point:393.1°Cat760mmHg
Flash Point:191.6°C
Density:1.189g/cm³
XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:238.099379685
Heavy Atom Count:18
Complexity:270

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)C(C2=CC3=CC=CC=C3O2)O

Technology Process of alpha-(4-Methylphenyl)-2-benzofuranmethanol

There total 7 articles about alpha-(4-Methylphenyl)-2-benzofuranmethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 41967-43-5
(1-benzofuran-2-yl)(4-methylphenyl)methanone

: 82158-21-2
p-methylphenyl(benzofuran-2-yl)methanol

Guidance literature:: With caesium carbonate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; bis(pinacol)diborane; copper(I) bromide; In toluene; at 90 ℃; for 12h; chemoselective reaction; Schlenk technique; Inert atmosphere;
DOI:10.1021/acs.joc.7b00596

Reference yield: 63.0%

: 261785-27-7
3-(o-acetoxyphenyl)-1-(p-methylphenyl)prop-2-yn-ol

: 82158-21-2
p-methylphenyl(benzofuran-2-yl)methanol

Guidance literature:: With palladium diacetate; potassium carbonate; lithium chloride; In N,N-dimethyl-formamide; at 80 ℃; for 16h;

Reference yield:

: 90-02-8
salicylaldehyde

: 82158-21-2
p-methylphenyl(benzofuran-2-yl)methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH, 2.) NaOMe / 1.) DMF, 70 deg C, 1.5 h, 2.) DMF, 70 deg C, 1.5 h

2: NaBH₄ / dioxane / 2 h / Ambient temperature

With sodium tetrahydroborate; sodium methylate; sodium hydride; In 1,4-dioxane;
DOI:10.1016/S0960-894X(99)00328-5