Quinfamide

Base Information

Chemical Name:Quinfamide
CAS No.:62265-68-3
Molecular Formula:C16H13Cl2NO4
Molecular Weight:354.19
Hs Code.:2934999090
European Community (EC) Number:263-478-1
UNII:O1ZB1046R1
DSSTox Substance ID:DTXSID90211320
Nikkaji Number:J18.454C
Wikipedia:Quinfamide
Wikidata:Q21098930
NCI Thesaurus Code:C72156
Metabolomics Workbench ID:153704
ChEMBL ID:CHEMBL2107014
Mol file:62265-68-3.mol

Synonyms:quinfamide;Win 400 14

Suppliers and Price of Quinfamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
QUINFAMIDE 95.00%
1G
$ 675.68

Total 47 raw suppliers

Chemical Property of Quinfamide

Chemical Property:

Vapor Pressure:3.37E-12mmHg at 25°C
Melting Point:145-146°C
Refractive Index:1.599
Boiling Point:551.3 °C at 760 mmHg
PKA:-0.01±0.20(Predicted)
Flash Point:287.2 °C
PSA：59.75000
Density:1.428g/cm³
LogP:3.64670
Storage Temp.:Hygroscopic, -20°C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:353.0221633
Heavy Atom Count:23
Complexity:459

Purity/Quality:

97% ^*data from raw suppliers

QUINFAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2=C(C=CC(=C2)OC(=O)C3=CC=CO3)N(C1)C(=O)C(Cl)Cl
Recent ClinicalTrials:Study to Evaluate Efficacy and Safety of a Double Treatment Plan Using a Combination of Mebendazole and Quinfamide for Treating Intestinal Helminthiasis and Amebiasis in the Mexican Population
Description Quinfamide is an amebicide indicated for the one-day treatment of subacute or chronic intestinal amebiasis. It acts by rendering the trophozoites of E. histolytica incapable of propagation.
Uses Quinfamide is an anti-amebic agent used to treat tropical parasitic infections. An antiamebic agent, used to treat tropical parasitic infections

Technology Process of Quinfamide

There total 3 articles about Quinfamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 527-69-5
2-furancarbonyl chloride

: 62265-67-2
1-dichloroacetyl-1,2,3,4-tetrahydro-quinolin-6-ol

: 7440-44-0
pyrographite

: 62265-68-3
quinfamide

Guidance literature:: With acetic acid; triethylamine; In methanol; chloroform; ethyl acetate;

Reference yield:

: 3373-00-0
6-hydroxy-1,2,3,4-tetrahydroquinoline

: 62265-68-3
quinfamide

Guidance literature:: Multi-step reaction with 2 steps

1: hexane; chloroform

2: acetic acid; triethylamine / methanol; chloroform; ethyl acetate

With acetic acid; triethylamine; In methanol; hexane; chloroform; ethyl acetate;