4-(((2-Phenyl-4-thiazolidinyl)carbonyl)amino)butanoic acid methyl ester monohydrochloride

Base Information

Chemical Name:4-(((2-Phenyl-4-thiazolidinyl)carbonyl)amino)butanoic acid methyl ester monohydrochloride
CAS No.:106086-23-1
Molecular Formula:C15H20 N2 O3 S . Cl H
Molecular Weight:0
Hs Code.:
DSSTox Substance ID:DTXSID60909904
Mol file:106086-23-1.mol

Synonyms:106086-23-1;4-(((2-Phenyl-4-thiazolidinyl)carbonyl)amino)butanoic acid methyl ester monohydrochloride;methyl 4-[(2-phenyl-1,3-thiazolidine-4-carbonyl)amino]butanoate;hydrochloride;DTXSID60909904;N-(4-Methoxy-4-oxobutyl)-2-phenyl-1,3-thiazolidine-4-carboximidic acid--hydrogen chloride (1/1)

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Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(((2-Phenyl-4-thiazolidinyl)carbonyl)amino)butanoic acid methyl ester monohydrochloride

Chemical Property:

Vapor Pressure:3.64E-12mmHg at 25°C
Boiling Point:550.5°Cat760mmHg
Flash Point:286.7°C
PSA：96.22000
Density:g/cm³
LogP:3.43070
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:344.0961414
Heavy Atom Count:22
Complexity:359

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC(=O)CCCNC(=O)C1CSC(N1)C2=CC=CC=C2.Cl

Technology Process of 4-(((2-Phenyl-4-thiazolidinyl)carbonyl)amino)butanoic acid methyl ester monohydrochloride

There total 4 articles about 4-(((2-Phenyl-4-thiazolidinyl)carbonyl)amino)butanoic acid methyl ester monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 106086-17-3
Methyl N-tert-butyloxycarbonyl-2-phenylthiazolidine-4-carbonyl-N'-γ-aminomethyl butyrate

: 106086-23-1
Methyl 2-phenylthiazolidine-4-carbonyl-N-γ-aminobutyrate hydrochloride

Guidance literature:: With hydrogenchloride; In 1,4-dioxane; at 10 ℃;
DOI:10.1007/BF01148643

Reference yield:

: 196930-46-8
(4R)-2-phenyl-1,3-thiazolidine-4-carboxylic acid

: 106086-23-1
Methyl 2-phenylthiazolidine-4-carbonyl-N-γ-aminobutyrate hydrochloride

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / Et₃N / dimethylformamide / 2 h / Ambient temperature

2: 81 percent / pyridine / dimethylformamide / 2 h / Ambient temperature

3: 91 percent / N-methylmorpholine / ethyl acetate / Ambient temperature

4: 67 percent / HCl / dioxane / 10 °C

With 4-methyl-morpholine; pyridine; hydrogenchloride; triethylamine; In 1,4-dioxane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1007/BF01148643

Reference yield:

: 106086-10-6
(4R)-3-(tert-butoxycarbonyl)-2-phenylthiazolidine-4-carboxylic acid

: 106086-23-1
Methyl 2-phenylthiazolidine-4-carbonyl-N-γ-aminobutyrate hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 81 percent / pyridine / dimethylformamide / 2 h / Ambient temperature

2: 91 percent / N-methylmorpholine / ethyl acetate / Ambient temperature

3: 67 percent / HCl / dioxane / 10 °C

With 4-methyl-morpholine; pyridine; hydrogenchloride; In 1,4-dioxane; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1007/BF01148643