(Z)-2-methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one

Base Information

Chemical Name:(Z)-2-methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one
CAS No.:67615-48-9
Molecular Formula:C14H12 O S
Molecular Weight:228.315
Hs Code.:
NSC Number:208870
DSSTox Substance ID:DTXSID90418317
Wikidata:Q82228795

Synonyms:MLS003107231;67615-48-9;NSC208870;DTXSID90418317;NSC-208870

Suppliers and Price of (Z)-2-methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of (Z)-2-methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one

Chemical Property:

Vapor Pressure:2.1E-05mmHg at 25°C
Boiling Point:361.2°Cat760mmHg
Flash Point:172.3°C
Density:1.167g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:228.06088618
Heavy Atom Count:16
Complexity:277

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=CC1=CC=CS1)C(=O)C2=CC=CC=C2
Isomeric SMILES:C/C(=C/C1=CC=CS1)/C(=O)C2=CC=CC=C2

Technology Process of (Z)-2-methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one

There total 3 articles about (Z)-2-methyl-1-phenyl-3-thiophen-2-ylprop-2-en-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 98-03-3
thiophene-2-carbaldehyde

: 93-55-0
1-phenyl-propan-1-one

: 67615-48-9
(E)-2-methyl-1-phenyl-3-(thiophen-2-yl)prop-2-en-1-one

Guidance literature:: With sodium ethanolate; In ethanol; at 0 ℃;

Reference yield: 18.0%

: 98-03-3
thiophene-2-carbaldehyde

: 673-32-5
1-Phenylprop-1-yne

: 67615-48-9
(E)-2-methyl-1-phenyl-3-(thiophen-2-yl)prop-2-en-1-one

Guidance literature:: With tetrafluoroboric acid diethyl ether; [bis(pyridine)iodine]⁺ tetrafluoroborate; In 1,2-dichloro-ethane; at 0 - 90 ℃; for 20h; Inert atmosphere; Darkness;
DOI:10.1039/c6ob02090a

Reference yield:

: 4393-06-0
1-Phenyl-2-propen-1-ol

: 636-72-6
2-thiophenemethanol

: 2-methyl-1-phenyl-3-(thiophen-2-yl)prop-2-en-1-one

: 67615-48-9
(E)-2-methyl-1-phenyl-3-(thiophen-2-yl)prop-2-en-1-one

Guidance literature:: With (4-Me)Triaz(NHPⁱPr₂)₂Mn(CO)₂Br; caesium carbonate; In tert-Amyl alcohol; at 135 ℃; for 24h; Overall yield = 71 percent; Overall yield = 81 mg; Inert atmosphere; Schlenk technique;
DOI:10.1016/j.tet.2021.132472