4-phenyl-N'-(1-quinolin-2-ylethyl)piperidine-1-carbothiohydrazide

Base Information

Chemical Name:4-phenyl-N'-(1-quinolin-2-ylethyl)piperidine-1-carbothiohydrazide
CAS No.:90504-24-8
Molecular Formula:C₂₃H₂₆N₄S
Molecular Weight:390.552
Hs Code.:
NSC Number:345295
DSSTox Substance ID:DTXSID90393357

Synonyms:90504-24-8;NSC345295;DTXSID90393357;HCMUXDYUCOJQDE-UHFFFAOYSA-N;4-phenyl-N'-(1-quinolin-2-ylethyl)piperidine-1-carbothiohydrazide;NSC-345295;4-Phenyl-N'-[1-(2-quinolinyl)ethyl]-1-piperidinecarbothiohydrazide #;N-[3-[1-[2-Quinolinyl]ethyl]hydrazinecarbothionyl]piperidine, 4-phenyl-

Suppliers and Price of 4-phenyl-N'-(1-quinolin-2-ylethyl)piperidine-1-carbothiohydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 4-phenyl-N'-(1-quinolin-2-ylethyl)piperidine-1-carbothiohydrazide

Chemical Property:

Boiling Point:545.5°Cat760mmHg
Flash Point:283.7°C
Density:1.206g/cm³
XLogP3:4.4
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:390.18781802
Heavy Atom Count:28
Complexity:499

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=NC2=CC=CC=C2C=C1)NNC(=S)N3CCC(CC3)C4=CC=CC=C4

Technology Process of 4-phenyl-N'-(1-quinolin-2-ylethyl)piperidine-1-carbothiohydrazide

There total 3 articles about 4-phenyl-N'-(1-quinolin-2-ylethyl)piperidine-1-carbothiohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 771-99-3
4-phenylpiperidine

: 90504-25-9
methyl 3-<1-(2-quinolyl)ethyl>hydrazinecarbodithioate

: 90504-24-8
4-Phenyl-piperidine-1-carbothioic acid N'-(1-quinolin-2-yl-ethyl)-hydrazide

Guidance literature:

Reference yield:

: 1011-47-8
1-quinolin-2-yl-ethanone

: 90504-24-8
4-Phenyl-piperidine-1-carbothioic acid N'-(1-quinolin-2-yl-ethyl)-hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 83 percent / propan-2-ol / 2 h / Heating

2: 75 percent / 1) sodium borohydride, 2) glacial acetic acid, H₂O / ethanol / 1.5 h

3: 59 percent

With sodium tetrahydroborate; water; acetic acid; In ethanol; isopropyl alcohol;

Reference yield:

: 90328-58-8
methyl 3-<1-(2-quinolyl)ethylidene>hydrazinecarbodithioate

: 90504-24-8
4-Phenyl-piperidine-1-carbothioic acid N'-(1-quinolin-2-yl-ethyl)-hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / 1) sodium borohydride, 2) glacial acetic acid, H₂O / ethanol / 1.5 h

2: 59 percent

With sodium tetrahydroborate; water; acetic acid; In ethanol;