Cinnamaldehyde azine

Base Information

• Chemical Name: Cinnamaldehyde azine
• CAS No.: 1568-11-2
• Molecular Formula: C18H16 N2
• Molecular Weight: 260.338
• Hs Code.: 2928000090
• European Community (EC) Number: 216-371-9
• NSC Number: 867
• Mol file: 1568-11-2.mol

Synonyms:Cinnamaldehyde azine;1568-11-2;EINECS 216-371-9;(E,E)-3-phenyl-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]prop-2-en-1-imine;2-Propenal, 3-phenyl-, 2-(3-phenyl-2-propen-1-ylidene)hydrazone;NSC867;(1E,2E)-1,2-Bis[(E)-3-phenylallylidene]hydrazine;(E)-3-phenylprop-2-enal azine;NSC 867;NSC-867;MIBXLDBZXACZIE-MKXOLOGGSA-N;STK037184;AKOS003595738;3-PHENYL-2-PROPENALDEHYDE, AZINE;(1E,2E)-bis[(2E)-3-phenylprop-2-en-1-ylidene]hydrazine;(1E,3E,5E,7E)-4,5-Diaza-1,8-diphenylocta-1,3,5,7-tetraene;(E)-3-phenyl-N-[(E)-[(E)-3-phenylprop-2-enylidene]amino]prop-2-en-1-imine

Chemical Property of Cinnamaldehyde azine

Chemical Property:

• Vapor Pressure: 7.46E-07mmHg at 25°C
• Melting Point: 176 °C
• Boiling Point: 419.3°Cat760mmHg
• PKA: 6.96±0.50(Predicted)
• Flash Point: 200°C
• PSA: 24.72000
• Density: 0.94g/cm³
• LogP: 4.46980
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 260.131348519
• Heavy Atom Count: 20
• Complexity: 318

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cinnamalazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C=CC=NN=CC=CC2=CC=CC=C2
• Isomeric SMILES: C1=CC=C(C=C1)/C=C/C=N/N=C/C=C/C2=CC=CC=C2

Technology Process of Cinnamaldehyde azine

There total 7 articles about Cinnamaldehyde azine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-phenyl-propenal (104-55-2) → N,N'-bis-(3-phenyl-allylidene)-hydrazine (1568-11-2)

Guidance literature:

With hydrazinium monoformate; at 25 ℃; for 0.0138889h;

DOI:10.1080/00397910600908835

Reference yield: 50.0%

3-phenyl-propenal (104-55-2) → N-[(E)-3-Phenyl-prop-2-en-(Z)-ylidene]-N'-[(E)-3-phenyl-prop-2-en-(E)-ylidene]-hydrazine (1568-11-2,13362-71-5,23632-46-4,59092-08-9)

Guidance literature:

With potassium carbonate; hydrazinium sulfate; In ethanol; at 0 ℃; for 48h;

DOI:10.1016/S0040-4020(01)96748-1

Reference yield:

6-methyl-4-oxo-9-(3-phenyl-allylidene)-6,7,8,9-tetrahydro-4H-pyrido[1,2-a]pyrimidine-3-carboxylic acid ethyl ester (93922-77-1) → N,N'-bis-(3-phenyl-allylidene)-hydrazine (1568-11-2) + 6-Methyl-4-oxo-6,7,8,9-tetrahydro-4H-pyrido<1,2-a>pyrimidine-3-carboxylic hydrazide (59333-99-2)

Guidance literature:

With hydrazine hydrate; In ethanol; for 6h; Yield given. Yields of byproduct given; Heating;

DOI:10.1055/s-1984-30899

upstream raw materials:

ethanol

3-phenyl-propenal

(E)-3-phenylpropenal

N-thioacetylaminoacetamidrazone

Downstream raw materials:

3-phenyl-propenal

hydrazine

[(CO)3Fe(N,N'-bis-(3-phenyl-allylidene)-hydrazine)Fe(CO)3]

1,5-distyryl-2H,6H-perhydrotriazolo-[1,2-a]triazole-3,7-dithione

Refernces

• 1、 Eshghi, Hossein,Hosseini, Mosayyeb. "Selective and convenient protection of aldehydes as azines under solvent-free conditions". experimental part. p. 636 - 638. Retrieved 2009/05/11.
• 2、 Nanjundaswamy,Pasha. "Selective protection of carbonyl compounds as azines and their facile regeneration". . p. 3161 - 3165. Retrieved 2007/10/03.