Rifamycin SV, 8-(1-pyrrolidinylmethyl)-

Base Information

• Chemical Name: Rifamycin SV, 8-(1-pyrrolidinylmethyl)-
• CAS No.: 4075-42-7
• Molecular Formula: C42H56N2O12
• Molecular Weight: 780.9002
• NSC Number: 144144
• Mol file: 4075-42-7.mol

Synonyms:PF-61;NSC 144144;NCI 144-144;Rifamycin SV, 8-(1-pyrrolidinylmethyl)-;4075-42-7;2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-2,4,12,16,18,20,22-heptamethyl-23-methoxy-8-(1-pyrrolidinylmethyl)-, 21-acetate;C42H56N2O12;NSC144144;C42-H56-N2-O12;NSC-144144;LS-64230

Chemical Property of Rifamycin SV, 8-(1-pyrrolidinylmethyl)-

Chemical Property:

• Vapor Pressure: 5.1E-34mmHg at 25°C
• Boiling Point: 890.2°C at 760 mmHg
• Flash Point: 492.2°C
• Density: 1.34g/cm³
• XLogP3: 5.8
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 13
• Rotatable Bond Count: 5
• Exact Mass: 780.38332523
• Heavy Atom Count: 56
• Complexity: 1500

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1C=CC=C(C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(OC=CC(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)CN5CCCC5)C
• Isomeric SMILES: CC1/C=C/C=C(/C(=O)NC2=C(C(=C3C(=C2O)C(=C(C4=C3C(=O)C(O4)(O/C=C/C(C(C(C(C(C(C1O)C)O)C)OC(=O)C)C)OC)C)C)O)O)CN5CCCC5)\C

Technology Process of Rifamycin SV, 8-(1-pyrrolidinylmethyl)-

There total 2 articles about Rifamycin SV, 8-(1-pyrrolidinylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrrolidine (123-75-1) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + rifamycin S (62623-68-1,76188-88-0,81203-58-9,101978-28-3,13553-79-2) → 3-Pyrrolidinomethyl-rifamycin SV (4075-42-7)

Guidance literature:

In tetrahydrofuran; water;

DOI:10.1021/jm00330a013

Reference yield:

→ C42H56N2O12 (4075-42-7)

Guidance literature:

Rifomycin S,Pyrrolidin,CH2O;

upstream raw materials:

pyrrolidine

formaldehyd

rifamycin S

Refernces