N-[2-(hydrazinylcarbonyl)phenyl]benzamide

Base Information

• Chemical Name: N-[2-(hydrazinylcarbonyl)phenyl]benzamide
• CAS No.: 92166-40-0
• Molecular Formula: C14H13 N3 O2
• Molecular Weight: 255.276
• Mol file: 92166-40-0.mol

Synonyms:Anthranilicacid, N-benzoyl-, hydrazide (7CI); 2-(Benzoylamino)benzoic hydrazide;N-Benzoylanthranilic hydrazide; N-[2-(Hydrazinylcarbonyl)phenyl]-benzamide; NSC509730

Chemical Property of N-[2-(hydrazinylcarbonyl)phenyl]benzamide

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.303g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-[2-(hydrazinylcarbonyl)phenyl]benzamide

There total 13 articles about N-[2-(hydrazinylcarbonyl)phenyl]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl 2-(benzamido)benzoate (7510-49-8) → N-[2-(hydrazinylcarbonyl)phenyl]benzamide (92166-40-0)

Guidance literature:

With hydrazine hydrate; In ethanol; for 15h; Heating;

DOI:10.1055/s-1984-31083

Reference yield: 52.0%

3-amino-2-phenylquinazolin-4(3H)-one (1904-60-5) → N-[2-(hydrazinylcarbonyl)phenyl]benzamide (92166-40-0)

Guidance literature:

With sodium hydroxide; 2-carbomethoxyaniline; In ethanol; for 2h; Heating;

Reference yield:

2-(Benzoylamino)benzoic Acid (579-93-1) → N-[2-(hydrazinylcarbonyl)phenyl]benzamide (92166-40-0)

Guidance literature:

With hydrazine hydrate; at 90 ℃; for 20h;

DOI:10.13005/ojc/320528

upstream raw materials:

2-phenyl-4H-3,1-benzoxazin-4-one

methyl 2-(benzamido)benzoate

ethanol

hydrazine hydrate

Refernces

• 1、 Altaf, Ataf Ali,Arshad, Muhammad Nadeem,Asiri, Abdullah M.,El-Bahy, Salah M.,Elnaggar, Ashraf Y.,Kausar, Naghmana,Kausar, Samia,Murtaza, Shahzad,Tatheer, Adina,Zaib Saleem, Rahman Shah. "Design, synthesis, crystal structure, in vitro cytotoxicity evaluation, density functional theory calculations and docking studies of 2-(benzamido) benzohydrazide derivatives as potent AChE and BChE inhibitors". . p. 154 - 167. Retrieved 2022/01/19.
• 2、 Arshad, Muhammad Nadeem,Ashraf, Zaman,Asim, Mulazim Hussain,Asiri, Abdullah M.,Javid, Noman,Kausar, Naghmana,Murtaza, Shahzad,Rashid, Robina. "Synthesis, characterization, biological evaluation and molecular docking studies of N-functionalized derivatives of 2-aminobenzohydrazide". . . Retrieved 2020/03/19.