7510-49-8

Usage

Uses

Used in Pharmaceutical Industry:
Methyl 2-(benzoylamino)benzoate is used as a precursor for the synthesis of various drugs for the treatment of diseases such as cancer and inflammation. Its analgesic and anti-inflammatory properties make it a valuable ingredient in many medications.
Used in Organic Synthesis:
Methyl 2-(benzoylamino)benzoate is used as an intermediate in organic synthesis for the production of other chemical compounds, contributing to the development of a wide range of products.
Used in Materials Science:
Methyl 2-(benzoylamino)benzoate has potential applications in the field of materials science, where it can be utilized in the development of new polymers and coatings, showcasing its versatility beyond the pharmaceutical domain.

Upstream product

• 110-86-1 pyridine 
• 98-88-4 benzoyl chloride 
• 134-20-3 2-carbomethoxyaniline 
• 14802-18-7 2-phenyl-1H-quinolin-4-one 
• 65-85-0 benzoic acid 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 932-90-1 Benzaldoxime 
• 610-94-6 2-bromobenzoic acid methyl ester 
• 55-21-0 benzamide 
• 91-56-5 indole-2,3-dione 
• 85-44-9 phthalic anhydride 
• 68061-82-5 methyl 2-(methyl(nitroso)amino)benzoate 
• 186581-53-3 diazomethane 
• 31588-18-8 3-hydroxy-2-phenyl-1H-quinolin-4-one 

Downstream Products

• 579-93-1 2-(Benzoylamino)benzoic Acid 
• 18543-22-1 2-benzoylaminobenzamide 
• 17240-30-1 2-phenylbenzo[d][1,3]thiazine-4-thione 
• 77642-40-1 N,N'-di-n-propylbenzamidine 
• 77651-73-1 2-phenyl-N-propyl-4-quinazolinamine 
• 77642-39-8 2-benzoylamino-N,N'-dipropylbenzamidine 
• 26060-02-6 2-phenyl-3-n-propylquinazoline-4(3H)-one 
• 22686-81-3 3-methyl-2-phenyl-4(3H)-quinazolinone 
• 77651-72-0 methyl(2-phenylquinazolin-4-yl)amine 
• 77642-41-2 N,N'-bis(2-methylpropyl)benzamidine 
• 77651-74-2 2-phenyl-N-(2-methylpropyl)-4-quinazolinamine 
• 77651-69-5 2-phenyl-3-(2-methylpropyl)-4(3H)-quinazolinone 
• 77651-75-3 butyl-(2-phenyl-quinazolin-4-yl)-amine 
• 77642-43-4 3-(3-dimethylaminopropyl)-2-phenyl-4(3H)-quinazolinone 

Relevant academic research and scientific papers

Synthesis, structural characterization and biological evaluation of mononuclear transition metal complexes of zwitterionic dehydroacetic acid N-aroylhydrazone ligand

Synthesis and characterization of mononuclear transition metal complexes viz., Co(II), Ni(II), Cu(II) and Zn(II) with a newly designed ligand, (E)-2-benzamido-N'-(1-(2-hydroxy-6-methyl-4-oxo-4H-pyran-3-yl) ethylidene) benzohydrazide (H2L) are r

Synthesis, characterization, biological evaluation and molecular docking studies of N-functionalized derivatives of 2-aminobenzohydrazide

In this paper, N-functionalized derivatives of methyl anthranilate (1–3) were prepared by reacting it with various acid chlorides to give amide derivatives (1–3) which were further converted to benzohydrazide derivatives (4–6) by reacting them with hydraz

Asymmetric Synthesis of N-N Axially Chiral Compounds by Phase-Transfer-Catalyzed Alkylations

N-N axially chiral skeletons are significant structural motifs in natural products, pharmaceuticals, and functional materials. Herein we disclose a method for the asymmetric synthesis of N-N axially chiral compounds by phase-transfer catalysis. A wide range of N-N axially chiral quinazolinone derivatives were prepared in high yields with excellent stereoselectivities. Furthermore, the synthetic utility of the protocol was proved by large-scale reaction and transformation of the product. Density functional theory calculations provide insight into the mechanism.

Novel O-acylated (E)-3-aryl-6,7-dihydrobenzisoxazol-4(5H)-one oximes targeting HSP90-HER2 axis in breast cancer cells

Novel O-acylated (E)-3-aryl-6,7-dihydrobenzisoxazol-4(5H)-one oximes were designed as potential HSP90 inhibitors. A series of the compounds was synthesized by oximation of (E)-3-aryl-6,7-dihydrobenzisoxazol-4(5H)-ones followed by O-acylation with acylamid

Tunable Electrosynthesis of Anthranilic Acid Derivatives via a C-C Bond Cleavage of Isatins

A facile and direct electrocatalytic C-C bond cleavage/functionalization reaction of isatins was developed. With isatins as the amino-attached C1 sources, a variety of aminobenzoates, and aminobenzamides were synthesized in moderate to good yields under mild conditions.

Design, synthesis, crystal structure, in vitro cytotoxicity evaluation, density functional theory calculations and docking studies of 2-(benzamido) benzohydrazide derivatives as potent AChE and BChE inhibitors

A series of hydrazone derivatives of 2-(benzamido) benzohydrazide was designed, synthesized, and characterized utilizing FTIR, NMR and UV spectroscopic techniques along with mass spectrometry. Compound 10 was also characterized through X-ray crystallograp

Synthesis of 2-Amino-1,3-dienes from Propargyl Carbonates via Palladium-Catalyzed Carbon-Nitrogen Bond Formation

A catalytic method to synthesize 1,3,-dienes from propargylic precursors is reported. This palladium-catalyzed carbon-nitrogen bond-forming reaction furnishes 2-amino-1,3-dienes in excellent yields (up to 98%) and shows a broad tolerance to functional group diversity. The reaction has been demonstrated for over 30 amine substrates, including anilines and indoles, and proceeds under mild neutral conditions. The resulting 1,3-dienes are of great synthetic interest because of their further reaction potential.

Para -Selective copper-catalyzed C(sp2)-H amidation/dimerization of anilides via a radical pathway

Copper-catalyzed amidation/dimerization of anilides via regioselective C(sp2)-H functionalization is achieved. The para-selective amidation is accomplished on the anilide aromatic ring via a radical pathway leading to C-N bond formation in the presence of ammonium persulfate as a radical source/oxidant for the copper catalyst. The developed protocol tolerates a wide range of anilide substrates. The regioselectivity is confirmed by single-crystal X-ray studies.

Potassium Carbonate Promoted C-N Coupling Reaction between Benzamides and Aryl Iodides

A practical and efficient method for N-arylation of benz-amides promoted by potassium carbonate in the presence of DMEDA was developed. The reaction was carried out without addition of any transition-metal catalyst to afford a variety of N-arylated products in moderate to good yields (up to 97%).

Latent Bronsted Base Solvent-Assisted Amide Formation from Amines and Acid Chlorides

Weakly basic amines, including even neutral amines such as nitroaniline and aminocarboxylic acids, react with acid chlorides very efficiently in N, N -dimethylacetamide (DMAC), without addition of a base, to give the corresponding amides in high yields. The role of DMAC and related solvents as latent Bronsted bases was studied in these amidation reactions. Less basic amines, such as aromatic amines, reacted with benzoyl chloride faster than more basic aliphatic amines.