N-[2-(dimethylamino)ethyl]-5-phenylquinoline-8-carboxamide hydrochloride (1:1)

Base Information

Chemical Name:N-[2-(dimethylamino)ethyl]-5-phenylquinoline-8-carboxamide hydrochloride (1:1)
CAS No.:113431-38-2
Molecular Formula:C₂₀H₂₁N₃O*ClH
Molecular Weight:355.867
Hs Code.:

Synonyms:8-Quinolinecarboxamide,N-[2-(dimethylamino)ethyl]-5-phenyl-, monohydrochloride (9CI)

Suppliers and Price of N-[2-(dimethylamino)ethyl]-5-phenylquinoline-8-carboxamide hydrochloride (1:1)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[2-(dimethylamino)ethyl]-5-phenylquinoline-8-carboxamide hydrochloride (1:1)

Chemical Property:

Vapor Pressure:1.35E-10mmHg at 25°C
Boiling Point:512°Cat760mmHg
Flash Point:263.4°C
Density:g/cm³

Purity/Quality:

Safty Information:

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Technology Process of N-[2-(dimethylamino)ethyl]-5-phenylquinoline-8-carboxamide hydrochloride (1:1)

There total 3 articles about N-[2-(dimethylamino)ethyl]-5-phenylquinoline-8-carboxamide hydrochloride (1:1) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 80938-67-6
4-methyl-[1,1'-biphenyl]-3-amine

: 113431-38-2
5-Phenyl-quinoline-8-carboxylic acid (2-dimethylamino-ethyl)-amide; hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: 64 percent / As₂O₅, conc. H₂SO₄ / 5 h / 160 - 165 °C

2: SeO₂ / Heating

3: 1.) 1,1'-carbonyldiimidazole / 1.) DMF, 20-50 deg C, 30 min, 2.) 15 min

With selenium(IV) oxide; arsenic(V) oxide; sulfuric acid; 1,1'-carbonyldiimidazole;
DOI:10.1021/jm00400a029

Reference yield:

: 113431-48-4
8-methyl-5-phenylquinoline

: 113431-38-2
5-Phenyl-quinoline-8-carboxylic acid (2-dimethylamino-ethyl)-amide; hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: SeO₂ / Heating

2: 1.) 1,1'-carbonyldiimidazole / 1.) DMF, 20-50 deg C, 30 min, 2.) 15 min

With selenium(IV) oxide; 1,1'-carbonyldiimidazole;
DOI:10.1021/jm00400a029