4-BroMobenzil

Base Information

• Chemical Name: 4-BroMobenzil
• CAS No.: 39229-12-4
• Molecular Formula: C14H9 Br O2
• Molecular Weight: 289.128
• Mol file: 39229-12-4.mol

Synonyms:Ethanedione,(4-bromophenyl)phenyl- (9CI); 4-Bromobenzil; NSC 39466; p-Bromobenzil

Chemical Property of 4-BroMobenzil

Chemical Property:

• Vapor Pressure: 9.85E-07mmHg at 25°C
• Melting Point: 86.5 °C
• Boiling Point: 403.9°Cat760mmHg
• Flash Point: 127.5°C
• PSA: 34.14000
• Density: 1.47g/cm³
• LogP: 3.51470
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

≥99.0% ^*data from raw suppliers

1,2-Ethanedione,1-(4-bromophenyl)-2-phenyl- 96% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-BroMobenzil

There total 59 articles about 4-BroMobenzil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.7%

4-bromobenzenecarbonitrile (623-00-7) + benzylamine (100-46-9) → 4-bromobenzil (39229-12-4)

Guidance literature:

With bis(1,5-cyclooctadiene)rhodium(I) trifluoromethanesulfonate; copper(I) trifluoroacetate; 3-chloro-benzenecarboperoxoic acid; In ethanol; N,N-dimethyl acetamide; at 45 ℃; for 4h; Reagent/catalyst; Solvent; Catalytic behavior;

Reference yield: 97.0%

1-bromo-4-phenylethynylbenzene (13667-12-4) → 4-bromobenzil (39229-12-4)

Guidance literature:

With potassium permanganate; tetraethylammonium bromide; sodium hydrogencarbonate; In dichloromethane; at 20 ℃; for 48h;

DOI:10.1021/ma048903q

Reference yield: 92.0%

4-bromobenzyl phenyl ketone (22421-88-1) → 4-bromobenzil (39229-12-4)

Guidance literature:

With oxygen; copper(II) acetate monohydrate; potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 0.5h; under 760.051 Torr;

DOI:10.1016/j.tetlet.2015.02.019

upstream raw materials:

ethyl bromide

1-(4-bromophenyl)-2-phenyl-ethan-1-one

(E)-4-bromostilbene

2-(4-bromophenyl)-2-hydroxy-1-phenylethan-1-one

Downstream raw materials:

1-(phenylglyoxaloyl)-4-(phenylethynyl)benzene

2,3-bis-(4-bromophenyl)quinoxaline

Refernces

• 1、 Shen, Duyi,Wang, Hongyan,Zheng, Yanan,Zhu, Xinjing,Gong, Peiwei,Wang, Bin,You, Jinmao,Zhao, Yulei,Chao, Mianran. "Catalyst-Free and Transition-Metal-Free Approach to 1,2-Diketones via Aerobic Alkyne Oxidation". . p. 5354 - 5361. Retrieved 2021/05/05.
• 2、 Song, Tao,Zhou, Xin,Wang, Xiaoxue,Xiao, Jianliang,Yang, Yong. "One-pot cascade synthesis of α-diketones from aldehydes and ketones in water by using a bifunctional iron nanocomposite catalyst". supporting information. p. 1955 - 1959. Retrieved 2021/03/26.