Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)butyl)-4-phenyl-

Base Information

Chemical Name:Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)butyl)-4-phenyl-
CAS No.:83409-13-6
Molecular Formula:C₃₂H₃₆N₄O₅
Molecular Weight:556.662
Hs Code.:
DSSTox Substance ID:DTXSID301003412

Synonyms:BRN 4624289;83409-13-6;Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)butyl)-4-phenyl-;C32H36N4O5;DTXSID301003412;C32-H36-N4-O5;LS-112911;3-[3-Methyl-1-oxo-1-(4-phenylpiperazin-1-yl)butan-2-yl]-2-(3,4,5-trimethoxyphenyl)quinazolin-4(3H)-one

Suppliers and Price of Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)butyl)-4-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)butyl)-4-phenyl-

Chemical Property:

Vapor Pressure:3.79E-21mmHg at 25°C
Boiling Point:729.7°C at 760 mmHg
Flash Point:395.1°C
Density:1.23g/cm³
XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:556.26857026
Heavy Atom Count:41
Complexity:915

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C(C(=O)N1CCN(CC1)C2=CC=CC=C2)N3C(=NC4=CC=CC=C4C3=O)C5=CC(=C(C(=C5)OC)OC)OC

Technology Process of Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)butyl)-4-phenyl-

There total 4 articles about Piperazine, 1-(3-methyl-1-oxo-2-(4-oxo-2-(3,4,5-trimethoxyphenyl)-3(4H)-quinazolinyl)butyl)-4-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 92-54-6
4-phenyl-1-piperazine

: 83409-26-1
3-Methyl-2-[4-oxo-2-(3,4,5-trimethoxy-phenyl)-4H-quinazolin-3-yl]-butyryl chloride

: 83409-13-6
3-[2-Methyl-1-(4-phenyl-piperazine-1-carbonyl)-propyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: In benzene; for 2h; Heating;

Reference yield:

: 40728-74-3
2-(3,4,5-trimethoxyphenyl)-4-H-benzo[d][1,3]oxazin-4-one

: 83409-13-6
3-[2-Methyl-1-(4-phenyl-piperazine-1-carbonyl)-propyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 3 steps

1: 70 percent / pyridine; H₂O / 10 h / Heating

2: SOCl₂ / benzene / 6 h / Heating

3: 68 percent / benzene / 2 h / Heating

With thionyl chloride; In pyridine; water; benzene;

Reference yield:

: 4521-61-3
3,4,5-Trimethoxybenzoyl chloride

: 83409-13-6
3-[2-Methyl-1-(4-phenyl-piperazine-1-carbonyl)-propyl]-2-(3,4,5-trimethoxy-phenyl)-3H-quinazolin-4-one

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 1) 0-5 deg C 2) 1h, room temperature

2: 70 percent / pyridine; H₂O / 10 h / Heating

3: SOCl₂ / benzene / 6 h / Heating

4: 68 percent / benzene / 2 h / Heating

With pyridine; thionyl chloride; In pyridine; water; benzene;