(E)-3-(2-(4-Methylphenyl)ethenylpyridine

Base Information

• Chemical Name: (E)-3-(2-(4-Methylphenyl)ethenylpyridine
• CAS No.: 6892-33-7
• Molecular Formula: C14H13 N
• Molecular Weight: 195.264
• Hs Code.: 2933399090
• Nikkaji Number: J2.989.115J,J303.393G
• Mol file: 6892-33-7.mol

Synonyms:(E)-3-(2-(4-Methylphenyl)ethenylpyridine;6892-33-7;(E)-3-[2-(4-Methylphenyl)ethenylpyridine;3-(4-Methylstyryl)pyridine;3-[(E)-4-Methylstyryl]pyridine;Pyridine, trans-3-[2-(4-methylphenyl)ethenyl]-

Chemical Property of (E)-3-(2-(4-Methylphenyl)ethenylpyridine

Chemical Property:

• Vapor Pressure: 0.000585mmHg at 25°C
• Boiling Point: 320.7°C at 760 mmHg
• Flash Point: 136.7°C
• PSA: 12.89000
• Density: 1.072g/cm³
• LogP: 3.56040
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 195.104799419
• Heavy Atom Count: 15
• Complexity: 201

Purity/Quality:

85.0-99.8% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)C=CC2=CN=CC=C2
• Isomeric SMILES: CC1=CC=C(C=C1)/C=C/C2=CN=CC=C2

Technology Process of (E)-3-(2-(4-Methylphenyl)ethenylpyridine

There total 9 articles about (E)-3-(2-(4-Methylphenyl)ethenylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-(2-(4-methylphenyl)ethynyl)pyridine (733035-88-6) → 3-[2-(4-methylphenyl)ethenyl]pyridine (6892-33-7)

Guidance literature:

With water; potassium ethyl xanthogenate; In N,N-dimethyl-formamide; at 130 ℃; for 12h; stereoselective reaction; Schlenk technique;

DOI:10.1039/C9CC00128J

Reference yield: 90.0%

3-Bromopyridine (626-55-1,163928-56-1) + 1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) → 3-[2-(4-methylphenyl)ethenyl]pyridine (6892-33-7)

Guidance literature:

With {1,3-bis[2,6-bis(propan-2-yl)phenyl]-1,3-dihydro-2H-imidazol-2-ylidene}dichloro(pyridine)palladium; caesium carbonate; In neat (no solvent); at 100 ℃; for 12h;

DOI:10.1080/00397911.2021.1919711

Reference yield: 45.0%

3-Chloropyridine (626-60-8) + 1-ethenyl-4-methylbenzene (622-97-9,24936-41-2) → 3-[2-(4-methylphenyl)ethenyl]pyridine (6892-33-7)

Guidance literature:

With potassium phosphate; C₂₄H₂₂ClN₃OPdSe; tetrabutylammomium bromide; In water; at 110 ℃; for 12h;

DOI:10.1039/c9ob01674k

upstream raw materials:

4-methyl-benzaldehyde

triphenyl-(pyridin-3-yl-methyl)-phosphonium chloride

3-chloromethylpyridinium chloride

triphenylphosphine

Downstream raw materials:

3-<4'-(2''-(3'''-pyridyl)vinyl)-α-styryl>pyridin