4-HYDROXYMETHYL-PIPERIDINE HCL

Base Information

• Chemical Name: 4-HYDROXYMETHYL-PIPERIDINE HCL
• CAS No.: 90748-01-9
• Molecular Formula: C₆H₁₃NO*ClH
• Molecular Weight: 151.636
• Mol file: 90748-01-9.mol

Synonyms:4-Piperidinemethanol,hydrochloride (7CI,9CI);

Chemical Property of 4-HYDROXYMETHYL-PIPERIDINE HCL

Chemical Property:

• Boiling Point: 198.2 °C at 760 mmHg
• Flash Point: 92.3 °C
• PSA: 32.26000
• Density: 0.951g/cm³
• LogP: 1.10910

Purity/Quality:

97% ^*data from raw suppliers

Piperidin-4-ylmethanolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXYMETHYL-PIPERIDINE HCL

There total 8 articles about 4-HYDROXYMETHYL-PIPERIDINE HCL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate (123855-51-6) → 4-piperidinemethanol hydrochloride (90748-01-9)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; at 20 ℃; for 3h;

Reference yield:

pyridine-4-methanol (586-95-8) → 4-piperidinemethanol hydrochloride (90748-01-9)

Guidance literature:

platinum (IV) oxide; In acetic acid;

Reference yield:

1-benzyl-4-piperidinemethanol hydrochloride + pyrographite (7440-44-0) → 4-piperidinemethanol hydrochloride (90748-01-9)

Guidance literature:

In ethanol;

upstream raw materials:

pyridine-4-methanol

pyrographite

tert-butyl 4-(hydroxymethyl)piperidin-1-carboxylate

isonipecotic acid

Downstream raw materials:

1-[4-(hydroxymethyl)piperidin-1-yl]ethan-1-one