3-(((4-Methoxyphenyl)methylene)amino)-2-phenyl-4(3H)-quinazolinone

Base Information

Chemical Name:3-(((4-Methoxyphenyl)methylene)amino)-2-phenyl-4(3H)-quinazolinone
CAS No.:73861-04-8
Molecular Formula:C22H17N3O2
Molecular Weight:355.396
Hs Code.:
ChEMBL ID:CHEMBL1289907

Synonyms:BRN 0835510;3-(((4-Methoxyphenyl)methylene)amino)-2-phenyl-4(3H)-quinazolinone;4(3H)-Quinazolinone, 3-(((4-methoxyphenyl)methylene)amino)-2-phenyl-;73861-04-8;SCHEMBL8497764;CHEMBL1289907;AKOS024352954;LS-141019

Suppliers and Price of 3-(((4-Methoxyphenyl)methylene)amino)-2-phenyl-4(3H)-quinazolinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(((4-Methoxyphenyl)methylene)amino)-2-phenyl-4(3H)-quinazolinone

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:541.289°C at 760 mmHg
Flash Point:281.162°C
Density:1.202g/cm³
XLogP3:4.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:355.132076794
Heavy Atom Count:27
Complexity:574

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=NN2C(=NC3=CC=CC=C3C2=O)C4=CC=CC=C4
Isomeric SMILES:COC1=CC=C(C=C1)/C=N/N2C(=NC3=CC=CC=C3C2=O)C4=CC=CC=C4

Technology Process of 3-(((4-Methoxyphenyl)methylene)amino)-2-phenyl-4(3H)-quinazolinone

There total 10 articles about 3-(((4-Methoxyphenyl)methylene)amino)-2-phenyl-4(3H)-quinazolinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1904-60-5
3-amino-2-phenylquinazolin-4(3H)-one

: 123-11-5
4-methoxy-benzaldehyde

: 73861-04-8
3-{[(4-methoxyphenyl)methylene]amino}-2-phenylquinazolin-4(3H)-one

Guidance literature:: In ethanol; at 70 - 80 ℃; for 0.333333h;
DOI:10.1055/s-1980-29177

Reference yield: 70.0%

: 56158-77-1
3-{[(4-hydroxyphenyl)methylene]amino}-2-phenylquinazolin-4(3H)-one

: 73861-04-8
3-{[(4-methoxyphenyl)methylene]amino}-2-phenylquinazolin-4(3H)-one

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 0 - 20 ℃; for 6h;
DOI:10.1007/s12272-013-0004-y

Reference yield:

: 118-92-3,159201-01-1,50816-84-7,80206-34-4,104809-47-4
anthranilic acid

: 73861-04-8
3-{[(4-methoxyphenyl)methylene]amino}-2-phenylquinazolin-4(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: pyridine / 3 h / 0 - 20 °C

2: pyridine; hydrazine hydrate / 0.33 h / 100 °C

3: acetic acid / ethanol / Reflux

With pyridine; hydrazine hydrate; acetic acid; In ethanol;