1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride

Base Information

Chemical Name:1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride
CAS No.:62717-42-4
Deprecated CAS:159795-65-0
Molecular Formula:C₁₆H₁₇NO₂*ClH
Molecular Weight:291.777
Hs Code.:
European Community (EC) Number:622-150-1
NSC Number:320959
UNII:WIV5R2G7VP
DSSTox Substance ID:DTXSID20936175
Pharos Ligand ID:UR6DTZSP15G4
ChEMBL ID:CHEMBL542700

Synonyms:1H-3-Benzazepine-7,8-diol, 2,3,4,5-tetrahydro-1-phenyl-;2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine;R-SK and F 38393;RSK and F 38393;SK and F 38393;SK and F-38393;SK and F38393;SKF 38393;SKF 38393 A;SKF 38393-A;SKF 38393A;SKF-38393;SKF38393

Suppliers and Price of 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
SKF38393Hydrochloride
250mg
$ 185.00

Sigma-Aldrich
(±)-SKF-38393 hydrochloride crystalline, ≥98% (HPLC)
1g
$ 1070.00

Sigma-Aldrich
(±)-SKF-38393 hydrochloride crystalline, ≥98% (HPLC)
100mg
$ 178.00

Sigma-Aldrich
(±)-SKF-38393 hydrochloride crystalline, ≥98% (HPLC)
500mg
$ 707.00

Medical Isotopes, Inc.
SKF38393HCl
100 mg
$ 625.00

DC Chemicals
SKF38393HCl >98%
1 g
$ 800.00

DC Chemicals
SKF38393HCl >98%
100 mg
$ 200.00

CSNpharm
SKF-38393HCl
50mg
$ 66.00

CSNpharm
SKF-38393HCl
100mg
$ 97.00

Crysdot
SKF38393hydrochloride 98+%
250mg
$ 190.00

Total 15 raw suppliers

Chemical Property of 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride

Chemical Property:

Melting Point:283-285 °C
PSA：52.49000
LogP:3.50620
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Solubility.:H2O: >5mg/mL
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:291.1026065
Heavy Atom Count:20
Complexity:291

Purity/Quality:

99%, ^*data from raw suppliers

SKF38393Hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 22-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1CNCC(C2=CC(=C(C=C21)O)O)C3=CC=CC=C3.Cl
Uses SKF 38393 Hydrochloride is a D1 receptor agonist.

Technology Process of 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride

There total 10 articles about 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 42738-59-0
(1S)-(-)-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

: 62717-94-6,62717-42-4
(-)-SKF 38393 hydrochloride

Guidance literature:: With hydrogenchloride; Heating;
DOI:10.1021/jm00086a016

Reference yield: 79.0%

: 62717-90-2
(1R)-(+)-7,8-dimethoxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepine

: 81702-42-3,62717-42-4
(+)-SKF 38393 hydrochloride

Guidance literature:: With hydrogenchloride; Heating;
DOI:10.1021/jm00086a016

Reference yield:

: 62717-93-5
(S)-3-benzyl-2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine hydrochloride

: 62717-94-6,62717-42-4
(-)-SKF 38393 hydrochloride

Guidance literature:: With hydrogen; palladium on activated charcoal; In methanol; ethyl acetate; at 25 ℃; for 2h; under 3102.9 Torr; Yield given;
DOI:10.1021/jm00348a017