N(6)-Hydroxymethyladenosine

Base Information

Chemical Name:N(6)-Hydroxymethyladenosine
CAS No.:98897-14-4
Molecular Formula:C₁₁H₁₅N₅O₅
Molecular Weight:297.271
Hs Code.:
DSSTox Substance ID:DTXSID60913006
Wikidata:Q82883514
Mol file:98897-14-4.mol

Synonyms:6-OHMEA;N(6)-hydroxymethyladenosine

Suppliers and Price of N(6)-Hydroxymethyladenosine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
N6-(Hydroxymethyl)adenosine(~90%)
100mg
$ 1070.00

Total 5 raw suppliers

Chemical Property of N(6)-Hydroxymethyladenosine

Chemical Property:

Vapor Pressure:1.41E-22mmHg at 25°C
Boiling Point:733.4°Cat760mmHg
Flash Point:397.3°C
PSA：145.78000
Density:1.98g/cm³
LogP:-2.12750
XLogP3:-1
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:9
Rotatable Bond Count:4
Exact Mass:297.10731860
Heavy Atom Count:21
Complexity:364

Purity/Quality:

97% ^*data from raw suppliers

N6-(Hydroxymethyl)adenosine(~90%) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)CO)O)O)NCO
Isomeric SMILES:C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)NCO
Uses N6-(Hydroxymethyl)adenosine is an intermediate with modified ribonucleoside formed by chemical oxidation of N6-methyladenosine (M275895) mediated by bicarbonate-activated hydrogen peroxide. N6-(Hydroxymethyl)adenosine is also reported as active mutagen.

Technology Process of N(6)-Hydroxymethyladenosine

There total 1 articles about N(6)-Hydroxymethyladenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 58-61-7
adenosine

: 98897-14-4
N(6)-hydroxymethyladenosine

: (2R,3R,4S,5R)-2-(6-Amino-purin-9-yl)-5-hydroxymethoxymethyl-tetrahydro-furan-3,4-diol

: (2R,3R,4S,5R)-2-[6-(Bis-hydroxymethyl-amino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol

Guidance literature:: In dimethylsulfoxide-d6; water; at 40 ℃; Product distribution; detection of different reaction products at different reaction times;
DOI:10.1002/mrc.1260270319