2-Chloroethyl trityl ether

Base Information

• Chemical Name: 2-Chloroethyl trityl ether
• CAS No.: 1235-23-0
• Molecular Formula: C21H19 Cl O
• Molecular Weight: 322.834
• European Community (EC) Number: 700-130-4
• NSC Number: 9178
• DSSTox Substance ID: DTXSID10924521
• Wikidata: Q72450350
• Mol file: 1235-23-0.mol

Synonyms:1235-23-0;2-Chloroethyl trityl ether;[2-chloroethoxy(diphenyl)methyl]benzene;Benzene, 1,1',1''-[(2-chloroethoxy)methylidyne]tris-;NSC 9178;C30H35NO4;1,1',1''-[(2-chloroethoxy)methanetriyl]tribenzene;NSC9178;SCHEMBL3573169;DTXSID10924521;2-Chloroethyltriphenylmethyl Ether;NSC-9178;C30-H35-N-O4;((2-Chloroethoxy)methanetriyl)tribenzene;EC 700-130-4

Chemical Property of 2-Chloroethyl trityl ether

Chemical Property:

• Melting Point: 132.0-133.5℃
• Boiling Point: 424.7°Cat760mmHg
• Flash Point: 204.1°C
• PSA: 9.23000
• Density: 1.138g/cm³
• LogP: 5.23390
• XLogP3: 5.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 322.1124429
• Heavy Atom Count: 23
• Complexity: 279

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)OCCCl

Technology Process of 2-Chloroethyl trityl ether

There total 3 articles about 2-Chloroethyl trityl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

trityl chloride (76-83-5) + 2-chloro-ethanol (107-07-3) → 2-triphenylmethoxy-1-chloroethane (1235-23-0)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; for 24h;

DOI:10.1016/j.bmc.2003.08.037

Reference yield:

bromo-triphenyl-methane (596-43-0) + 2-chloro-ethanol (107-07-3) → 2-triphenylmethoxy-1-chloroethane (1235-23-0)

Guidance literature:

Reference yield:

→ 2-triphenylmethoxy-1-chloroethane (1235-23-0)

Guidance literature:

entspr. Chlorid, Cl-CH2-CH2-OH;

upstream raw materials:

trityl chloride

2-chloro-ethanol

bromo-triphenyl-methane

Downstream raw materials:

1-(2-trityloxy-ethyl)-piperidine

1,9-di(triphenylmethoxy)-3,7-dioxanonane

11-{4-[2-(2-tritiloxiethoxy)ethyl]piperazine-1-yl}dibenzo[b,f][1,4]thiazepine