Deoxyhypusine

Base Information

Chemical Name:Deoxyhypusine
CAS No.:82543-85-9
Molecular Formula:C₁₀H₂₃N₃O₂
Molecular Weight:217.312
Hs Code.:
DSSTox Substance ID:DTXSID20231839
Nikkaji Number:J494.042C
Wikidata:Q27104743
Metabolomics Workbench ID:41148
Mol file:82543-85-9.mol

Synonyms:deoxyhypusine;N(6)-(4-aminobutyl)lysine

Suppliers and Price of Deoxyhypusine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Deoxyhypusine

Chemical Property:

Vapor Pressure:3.04E-07mmHg at 25°C
Boiling Point:392.2°C at 760 mmHg
Flash Point:191°C
PSA：101.37000
Density:1.061g/cm³
LogP:1.68860
XLogP3:-2.8
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:10
Exact Mass:217.17902698
Heavy Atom Count:15
Complexity:165

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CCNCCCCN)CC(C(=O)O)N
Isomeric SMILES:C(CCNCCCCN)C[C@@H](C(=O)O)N

Technology Process of Deoxyhypusine

There total 11 articles about Deoxyhypusine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.3%

: C₂₀H₃₉N₃O₆

: 82543-85-9
deoxyhypusine

Guidance literature:: With hydrogenchloride; In ethanol; at 5 - 25 ℃; for 12h;

Reference yield:

: 189280-15-7
tert-butyl(2S,9R)-11-[(benzyloxycarbonyl)amino]-2-[(tert-butoxycarbonyl)amino]-9-hydroxy-7-(benzyloxycarbonyl)-7-azaundecanoate

: 82543-85-9
deoxyhypusine

Guidance literature:: Multi-step reaction with 3 steps

1: 67 percent / trifluoroacetic acid, triethylsilane / CH₂Cl₂ / 23 h / Ambient temperature

2: 58 percent / 9percent aq. Na₂CO₃ / dimethylformamide / 21 h / Ambient temperature

3: 1.) piperidine, 2.) phenol, pentamethylbenzene, triisopropylsilane, 30percent HBr/HOAc / 1.) DMF, 2.) TFA, RT

With piperidine; triethylsilane; chlorotriisopropylsilane; pentamethylbenzene,; hydrogen bromide; sodium carbonate; acetic acid; trifluoroacetic acid; phenol; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm980389p

Reference yield:

: (2S,9R)-2-[(tert-Butoxycarbonyl)amino]-11-amino-9-hydroxy-7-azaundecanoic Acid tert-Butyl Ester, Diacetate Salt

: 82543-85-9
deoxyhypusine

Guidance literature:: Multi-step reaction with 4 steps

1: 50 percent / aq. KHCO₃ / diethyl ether / 4 h / Ambient temperature

2: 67 percent / trifluoroacetic acid, triethylsilane / CH₂Cl₂ / 23 h / Ambient temperature

3: 58 percent / 9percent aq. Na₂CO₃ / dimethylformamide / 21 h / Ambient temperature

4: 1.) piperidine, 2.) phenol, pentamethylbenzene, triisopropylsilane, 30percent HBr/HOAc / 1.) DMF, 2.) TFA, RT

With piperidine; triethylsilane; chlorotriisopropylsilane; pentamethylbenzene,; hydrogen bromide; sodium carbonate; potassium hydrogencarbonate; acetic acid; trifluoroacetic acid; phenol; In diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm980389p