Ethyl 3-(diethylamino)propanoate

Base Information

• Chemical Name: Ethyl 3-(diethylamino)propanoate
• CAS No.: 5515-83-3
• Molecular Formula: C9H19 N O2
• Molecular Weight: 173.255
• Hs Code.: 2922499990
• European Community (EC) Number: 226-859-3
• NSC Number: 163292
• DSSTox Substance ID: DTXSID10203661
• Nikkaji Number: J210.565I
• Wikidata: Q83077074
• Mol file: 5515-83-3.mol

Synonyms:ethyl 3-(diethylamino)propanoate;5515-83-3;Ethyl 3-(diethylamino)propionate;Ethyl 3-diethylaminopropionate;EINECS 226-859-3;AI3-13198;EC 226-859-3;ETHYL beta-DIETHYLAMINO PROPIONATE;ethyl3-(diethylamino)propanoate;SCHEMBL9319516;DTXSID10203661;ethyl 3-(diethylamino) propionate;MFCD00041349;NSC163292;N,N-Diethyl-beta-alanine ethyl ester;AKOS005216601;Ethyl 3-(N,N-Diethylamino)propionate;NSC 163292;NSC-163292;beta-Alanine, N,N-diethyl-, ethyl ester;.beta.-Alanine, N,N-dimethyl-, ethyl ester;FT-0615599;FT-0625758;FT-0626269

Chemical Property of Ethyl 3-(diethylamino)propanoate

Chemical Property:

• Refractive Index: 1.4253 (estimate)
• Boiling Point: 215.5°Cat760mmHg
• Flash Point: 71.7°C
• PSA: 29.54000
• Density: 0.922g/cm³
• LogP: 1.28140
• XLogP3: 1.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 173.141578849
• Heavy Atom Count: 12
• Complexity: 122

Purity/Quality:

99.9% ^*data from raw suppliers

Ethyl3-(Diethylamino)propanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CCC(=O)OCC

Technology Process of Ethyl 3-(diethylamino)propanoate

There total 21 articles about Ethyl 3-(diethylamino)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

diethylamine (109-89-7) + ethyl acrylate (140-88-5,9003-32-1) → ethyl 3-(diethylamino)propionate (5515-83-3)

Guidance literature:

With copper diacetate; In water; at 20 ℃; for 12h;

DOI:10.1055/s-2003-42125

Reference yield: 95.0%

triethylamine (121-44-8) + ethyl acrylate (140-88-5,9003-32-1) → ethyl 3-(diethylamino)propionate (5515-83-3)

Guidance literature:

With acetic acid; palladium dichloride; In N,N-dimethyl-formamide; at 70 ℃; for 48h;

DOI:10.1002/ejoc.200700369

Reference yield: 92.0%

2-methylenebutyric acid (3586-58-1,62607-09-4) + diethylamine (109-89-7) → ethyl 3-(diethylamino)propionate (5515-83-3)

Guidance literature:

With 10H-phenothiazine; at 0 - 80 ℃; for 5h; Temperature; Reagent/catalyst;

upstream raw materials:

3-diethylaminopropionitrile

ethanol

ethyl 3-chloropropanoate

diethylamine

Downstream raw materials:

3-diethylamino-1,1-diphenyl-1-propanol hydrochloride

3-diethylamino-1,1-diphenyl-propan-1-ol

3-diethylamino-propan-1-ol

β-Diethylaminopropionhydrazid

Refernces

• 1、 Li, Junqiao,Lu, Wei,Li, Weifeng,Liang, Xuezheng. "Synthesis and catalytic activity of porous polymer containing ionic liquid structures". . p. 840 - 846. Retrieved 2016/12/07.
• 2、 Vanderveen, Jesse R.,Durelle, Jeremy,Jessop, Philip G.. "Design and evaluation of switchable-hydrophilicity solvents". . p. 1187 - 1197. Retrieved 2014/03/21.