4,N-DIMETHYL-N-PHENYL-BENZENESULFONAMIDE

Base Information

• Chemical Name: 4,N-DIMETHYL-N-PHENYL-BENZENESULFONAMIDE
• CAS No.: 599-62-2
• Molecular Formula: C14H15NO2S
• Molecular Weight: 261.345
• Hs Code.: 2935009090
• Mol file: 599-62-2.mol

Synonyms:4-methyl-N-methyl-N-phenylbenzenesulfonamide;Benzenesulfonamide,N,4-dimethyl-N-phenyl;N-phenyl-N-methyl-toluenesulfonamide;4,N-dimethyl-N-phenyl-benzenesulfonamide;N-methyl-toluene-4-sulfonanilide;Benzenesulfonamide, N,4-dimethyl-N-phenyl-;Benzenesulfonamide,4-dimethyl-N-phenyl;N-methyl-N-phenyl-p-toluenesulfonamide;

Chemical Property of 4,N-DIMETHYL-N-PHENYL-BENZENESULFONAMIDE

Chemical Property:

• Vapor Pressure: 2.41E-06mmHg at 25°C
• Boiling Point: 391.7°C at 760 mmHg
• Flash Point: 190.7°C
• PSA: 45.76000
• Density: 1.224g/cm³
• LogP: 3.90090

Purity/Quality:

99% ^*data from raw suppliers

N-METHYL-P-TOLUENESULFONANILIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4,N-DIMETHYL-N-PHENYL-BENZENESULFONAMIDE

There total 36 articles about 4,N-DIMETHYL-N-PHENYL-BENZENESULFONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

triphenylbismuthane (603-33-8) + N-methyl-p-toluenesulfonylamide (640-61-9) → N-methyl-N-phenyltoluenesulfonamide (599-62-2)

Guidance literature:

With pyridine; copper diacetate; In dichloromethane; for 6h; Ambient temperature;

DOI:10.1016/S0040-4039(96)02116-8

Reference yield: 94.0%

p-toluenesulfonyl chloride (98-59-9) + N-methylaniline (100-61-8) → N-methyl-N-phenyltoluenesulfonamide (599-62-2)

Guidance literature:

With silica gel; at 20 ℃;

DOI:10.1021/jo5011334

Reference yield: 94.0%

phenyl toluenesulfonamide (68-34-8) + methyl iodide (74-88-4) → N-methyl-N-phenyltoluenesulfonamide (599-62-2)

Guidance literature:

With potassium hydroxide; 3-butyl-1-methyl-1H-imidazol-3-ium hexafluorophosphate; at 20 ℃; for 1h;

DOI:10.1080/00304940409458677

upstream raw materials:

diazomethane

phenyl toluenesulfonamide

trimethylphenylammonium hydroxide

N,N-dimethyl-aniline

Downstream raw materials:

toluene-4-sulfonic acid-(N-methyl-2-nitro-anilide)

toluene-4-sulfonic acid-(N-methyl-4-nitro-anilide)

N-methylaniline

5-Methyl-2-benzoesaeure

Refernces

• 1、 Firoozi, Somayeh,Hosseini-Sarvari, Mona. "Nanosized CdS as a Reusable Photocatalyst: The Study of Different Reaction Pathways between Tertiary Amines and Aryl Sulfonyl Chlorides through Visible-Light-Induced N-Dealkylation and C-H Activation Processes". . p. 2117 - 2134. Retrieved 2021/02/05.
• 2、 Heredia, Micaela D.,Guerra, Walter D.,Barolo, Silvia M.,Fornasier, Santiago J.,Rossi, Roberto A.,Budén, Mariá E.. "Transition-Metal-Free and Visible-Light-Mediated Desulfonylation and Dehalogenation Reactions: Hantzsch Ester Anion as Electron and Hydrogen Atom Donor". supporting information. p. 13481 - 13494. Retrieved 2020/12/15.