2,4-Dichloro-6-(propan-2-yl)pyrimidine

Base Information

• Chemical Name: 2,4-Dichloro-6-(propan-2-yl)pyrimidine
• CAS No.: 89938-05-6
• Molecular Formula: C7H8 Cl2 N2
• Molecular Weight: 191.06
• European Community (EC) Number: 868-415-7
• NSC Number: 58570
• DSSTox Substance ID: DTXSID60289016
• Wikidata: Q82026165
• ChEMBL ID: CHEMBL1997248
• Mol file: 89938-05-6.mol

Synonyms:89938-05-6;2,4-dichloro-6-(propan-2-yl)pyrimidine;2,4-dichloro-6-isopropylpyrimidine;2,4-dichloro-6-propan-2-ylpyrimidine;NSC58570;SCHEMBL1706547;CHEMBL1997248;DTXSID60289016;QOPLCURPYPOIIB-UHFFFAOYSA-N;NSC-58570;AKOS013907520;SB56227;NCI60_004425;CS-0057836;E80925;EN300-136140;Z1238571439

Chemical Property of 2,4-Dichloro-6-(propan-2-yl)pyrimidine

Chemical Property:

• Vapor Pressure: 0.0506mmHg at 25°C
• Boiling Point: 243.3°Cat760mmHg
• Flash Point: 124.4°C
• PSA: 25.78000
• Density: 1.274g/cm³
• LogP: 2.90680
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 190.0064537
• Heavy Atom Count: 11
• Complexity: 130

Purity/Quality:

99%, ^*data from raw suppliers

2,4-Dichloro-6-(propan-2-yl)pyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C1=CC(=NC(=N1)Cl)Cl

Technology Process of 2,4-Dichloro-6-(propan-2-yl)pyrimidine

There total 6 articles about 2,4-Dichloro-6-(propan-2-yl)pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2,4-dihydroxy-6-isopropylpyrimidine (58289-27-3) → 2,4-dichloro-6-(propan-2-yl)pyrimidine (89938-05-6)

Guidance literature:

2,4-dihydroxy-6-isopropylpyrimidine; With N,N-dimethyl-aniline; trichlorophosphate; for 4h; Reflux;

With sodium hydrogencarbonate; In chloroform; water;

Reference yield: 58.0%

2,4,6-trichloropyrimidine (3764-01-0) + isopropylmagnesium chloride (1068-55-9) → 2,4-dichloro-6-(propan-2-yl)pyrimidine (89938-05-6)

Guidance literature:

With copper(l) iodide; In tetrahydrofuran; at -20 - 0 ℃; for 2h; Inert atmosphere;

Reference yield: 50.0%

2,4-dichloro-6-ethylpyrimidine (6554-65-0) + methyl iodide (74-88-4) → 2,4-dichloro-6-(propan-2-yl)pyrimidine (89938-05-6)

Guidance literature:

2,4-dichloro-6-ethylpyrimidine; With lithium diisopropyl amide; In tetrahydrofuran; at -70 ℃; for 0.5h; Inert atmosphere;

methyl iodide; In tetrahydrofuran; at -70 ℃; for 2h; Inert atmosphere;

upstream raw materials:

2,4-dihydroxy-6-isopropylpyrimidine

2,6-Dichloropyrimidine

isobutyric Acid

2,4,6-trichloropyrimidine

Downstream raw materials:

2-chloro-6-isopropylpyrimidin-4-amine

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 89938-05-6 2,4-Dichloro-6-isopropylpyrimidine

Send

Send

Metric Ton KG G Pound L ML

Send

Send