ipsapirone

Base Information

Chemical Name:ipsapirone
CAS No.:92589-98-5
Molecular Formula:C₁₉H₂₃N₅O₃S*ClH
Molecular Weight:437.95
Hs Code.:
Mol file:92589-98-5.mol

Synonyms:1,2-Benzisothiazol-3(2H)-one,2-[4-[4-(2-pyrimidinyl)-1-piperazinyl]butyl]-, 1,1-dioxide, monohydrochloride(9CI); BAY-q 7821; Ipsapirone hydrochloride; TVX-Q 7821

Suppliers and Price of ipsapirone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of ipsapirone

Chemical Property:

Melting Point:221-222°
Boiling Point:629.8°Cat760mmHg
Flash Point:334.7°C
PSA：95.09000
Density:1.345g/cm³
LogP:2.24510

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Anti-anxiety agent .

Technology Process of ipsapirone

There total 4 articles about ipsapirone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 103564-59-6
N-[4-bromobutyl]saccharin

: 94021-22-4
1-(2-pyrimidyl)piperazine dihydrochloride

: 92589-98-5
ipsapirone hydrochloride

Guidance literature:: N-[4-bromobutyl]saccharin; 1-(2-pyrimidyl)piperazine dihydrochloride; With tetrabutylammomium bromide; potassium carbonate; In N,N-dimethyl-formamide; for 0.0166667h; Microwave irradiation;

With hydrogenchloride; In 1,4-dioxane; acetone;
DOI:10.1002/jhet.3520

Reference yield: 77.0%

: 20980-22-7
N-(2-pyridinyl)piperazine

: 103564-59-6
N-[4-bromobutyl]saccharin

: 92589-98-5
ipsapirone hydrochloride

Guidance literature:: N-(2-pyridinyl)piperazine; N-[4-bromobutyl]saccharin; With tetrabutylammomium bromide; potassium carbonate; for 0.0416667h; Sealed tube; Microwave irradiation;

With hydrogenchloride; In 1,4-dioxane; acetone; pH=2 - 3;
DOI:10.1016/j.bmcl.2021.128028

Reference yield: 50.0%

: 110-52-1
1,4-dibromo-butane

: 94021-22-4
1-(2-pyrimidyl)piperazine dihydrochloride

: 81-07-2
saccharin

: 92589-98-5
ipsapirone hydrochloride

Guidance literature:: 1,4-dibromo-butane; saccharin; With tetrabutylammomium bromide; potassium carbonate; In N,N-dimethyl-formamide; for 0.0138889h; Microwave irradiation;

1-(2-pyrimidyl)piperazine dihydrochloride; In N,N-dimethyl-formamide; for 0.0333333h; Microwave irradiation;

With hydrogenchloride; In 1,4-dioxane; acetone; Concentration; Solvent; Reagent/catalyst; Time; Catalytic behavior;
DOI:10.1002/jhet.3520