N-(2-Oxo-1,2-diphenylethyl)-2-phenylacetamide

Base Information

• Chemical Name: N-(2-Oxo-1,2-diphenylethyl)-2-phenylacetamide
• CAS No.: 6942-04-7
• Molecular Formula: C22H19NO2
• Molecular Weight: 329.398
• NSC Number: 631606,57623
• DSSTox Substance ID: DTXSID90288794
• Mol file: 6942-04-7.mol

Synonyms:N-(2-Oxo-1,2-diphenylethyl)-2-phenylacetamide;Acetamide, N-desyl-.alpha.-phenyl-;NSC631606;6942-04-7;NSC57623;NCIOpen2_007400;DTXSID90288794;N-(2-OXO-1,2-DIPHENYL-ETHYL)-2-PHENYL-ACETAMIDE;NSC-57623;NSC-631606

Chemical Property of N-(2-Oxo-1,2-diphenylethyl)-2-phenylacetamide

Chemical Property:

• Vapor Pressure: 2.42E-13mmHg at 25°C
• Boiling Point: 577.6°C at 760 mmHg
• Flash Point: 203.9°C
• Density: 1.167g/cm³
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 6
• Exact Mass: 329.141578849
• Heavy Atom Count: 25
• Complexity: 429

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)CC(=O)NC(C2=CC=CC=C2)C(=O)C3=CC=CC=C3

Technology Process of N-(2-Oxo-1,2-diphenylethyl)-2-phenylacetamide

There total 2 articles about N-(2-Oxo-1,2-diphenylethyl)-2-phenylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-amino-1,2-diphenylethanone (3723-23-7) + phenylacetyl chloride (103-80-0) → phenyl-acetic acid-(α'-oxo-bibenzyl-α-ylamide) (6942-04-7)

Guidance literature:

DOI:10.1021/ja01140a063

Reference yield:

→ phenyl-acetic acid-(α'-oxo-bibenzyl-α-ylamide) (6942-04-7)

Guidance literature:

2-Benzyliden-(2H)-oxazolin-5-on u. Benzol m. Hilfe v. AlCl3;

Reference yield:

phenyl-acetic acid-(α'-oxo-bibenzyl-α-ylamide) (6942-04-7) → 2-benzyl-4,5-diphenyl-1H-imidazole (56796-43-1)

Guidance literature:

With ammonium acetate; acetic acid;

DOI:10.1021/ja01140a063

upstream raw materials:

2-amino-1,2-diphenylethanone

phenylacetyl chloride

Downstream raw materials:

2-benzyl-4,5-diphenyl-1H-imidazole

1,2-dibenzyl-4,5-diphenyl-1H-imidazole