Clidafidine

Base Information

• Chemical Name: Clidafidine
• CAS No.: 33588-20-4
• Molecular Formula: C9H8 Cl2 N2 O
• Molecular Weight: 0
• Mol file: 33588-20-4.mol

Synonyms:Oxazolidine,2-[(2,6-dichlorophenyl)imino]- (8CI); Clidafidine; Ursonarkon

Chemical Property of Clidafidine

Chemical Property:

• Vapor Pressure: 0.00112mmHg at 25°C
• Boiling Point: 300.5°Cat760mmHg
• Flash Point: 135.5°C
• PSA: 33.62000
• Density: 1.49g/cm³
• LogP: 2.92950

Purity/Quality:

CLIDAFIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Clidafidine

There total 3 articles about Clidafidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

ethanolamine (141-43-5) + 2,6-dichlorophenylisocyanate (39920-37-1) → (2,6-dichloro-phenyl)-(4,5-dihydro-oxazol-2-yl)-amine (33588-20-4)

Guidance literature:

Multistep reaction; (i) AcOEt, (ii) HgO, benzene, EtOH;

DOI:10.1021/jm00235a020

Reference yield:

→ (2,6-dichloro-phenyl)-(4,5-dihydro-oxazol-2-yl)-amine (33588-20-4)

Guidance literature:

2,6-Dichlorphenylisocyaniddichlorid, Aethanolamin.;

Reference yield:

→ (2,6-dichloro-phenyl)-(4,5-dihydro-oxazol-2-yl)-amine (33588-20-4)

Guidance literature:

aus 2,6-Dichlorphenylisocyanid-dichlorid, H2NCH2CH2OH;

upstream raw materials:

ethanolamine

2,6-dichlorophenylisocyanate