3-Phenyl-1-piperidino-2-propyn-1-one

Base Information

Chemical Name:3-Phenyl-1-piperidino-2-propyn-1-one
CAS No.:14143-92-1
Molecular Formula:C14H15 N O
Molecular Weight:213.279
Hs Code.:2933399090
NSC Number:203232
UNII:W23M69Z3Y2
DSSTox Substance ID:DTXSID50161731
Nikkaji Number:J51.149H
Wikidata:Q83030177
ChEMBL ID:CHEMBL1998048
Mol file:14143-92-1.mol

Synonyms:3-Phenyl-1-piperidino-2-propyn-1-one;14143-92-1;Piperidine, 1-(1-oxo-3-phenyl-2-propynyl)-;2-Propyn-1-one, 3-phenyl-1-piperidino-;3-phenyl-1-piperidin-1-ylprop-2-yn-1-one;Piperidine, 1-(phenylpropioloyl)-;NSC-203232;1-(Phenylpropioloyl)piperidine;3-phenyl-1-(piperidin-1-yl)prop-2-yn-1-one;NSC 203232;BRN 1245009;NSC203232;1-(Phenylpropiolyl)piperidine;Piperidine, 1-phenpropioloyl-;Piperidine, 1-(1-oxo-3-phenyl-2-propynyl)- (9CI);CHEMBL1998048;SCHEMBL24416093;DTXSID50161731;UZCUKRQNGYSLLG-UHFFFAOYSA-N;W23M69Z3Y2;1-(3-Phenyl-2-propynoyl)piperidine #;1-[(Phenylacetylenyl)carbonyl]pipenidine;NCI60_001709;2-Propyn-1-one, 3-phenyl-1-(1-piperidinyl)-

Suppliers and Price of 3-Phenyl-1-piperidino-2-propyn-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 3-Phenyl-1-piperidino-2-propyn-1-one

Chemical Property:

Vapor Pressure:0.000117mmHg at 25°C
Boiling Point:335.8°C at 760 mmHg
Flash Point:141°C
PSA：20.31000
Density:1.12g/cm³
LogP:1.98850
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:213.115364102
Heavy Atom Count:16
Complexity:297

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCN(CC1)C(=O)C#CC2=CC=CC=C2

Technology Process of 3-Phenyl-1-piperidino-2-propyn-1-one

There total 20 articles about 3-Phenyl-1-piperidino-2-propyn-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 110-89-4
piperidine

: (E)-4-oxo-4-phenylbut-2-en-2-yl 3-phenylpropiolate

: 14143-92-1
3-phenyl-1-(piperidin-1-yl)prop-2-yn-1-one

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 0.0833333h;

Reference yield: 96.0%

: 110-89-4
piperidine

: 637-44-5
phenylpropyolic acid

: 14143-92-1
3-phenyl-1-(piperidin-1-yl)prop-2-yn-1-one

Guidance literature:: phenylpropyolic acid; With N-(2,2-dimethyl-1,3-dioxolan-4-ylmethyl)-N-ethynylmethanesulfonamide; In dichloromethane; at 20 ℃;

piperidine; In dichloromethane;

Reference yield: 96.0%

: 110-89-4
piperidine

: 201230-82-2
carbon monoxide

: 536-74-3
phenylacetylene

: 14143-92-1
3-phenyl-1-(piperidin-1-yl)prop-2-yn-1-one

Guidance literature:: With palladium 10% on activated carbon; oxygen; tetra-(n-butyl)ammonium iodide; In 1,4-dioxane; at 80 ℃; for 14h; Autoclave;
DOI:10.1002/adsc.201200041