(1,1'-Biphenyl)-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester

Base Information

Chemical Name:(1,1'-Biphenyl)-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester
CAS No.:61888-75-3
Molecular Formula:C₁₆H₁₅ClO₃
Molecular Weight:290.746
Hs Code.:2922299090
DSSTox Substance ID:DTXSID50210899
Wikidata:Q83085729
ChEMBL ID:CHEMBL3244541
Mol file:61888-75-3.mol

Synonyms:61888-75-3;BRN 2132238;(1,1'-Biphenyl)-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester;Ethyl 4'-chloro-5-hydroxy-3-biphenylacetate;Ethyl 4'-chloro-5-hydroxy-(1,1'-biphenyl)-3-acetate;4'-Chloro-5-hydroxy-(1,1'-biphenyl)-3-acetic acid ethyl ester;CHEMBL3244541;DTXSID50210899;LS-44042

Suppliers and Price of (1,1'-Biphenyl)-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (1,1'-Biphenyl)-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester

Chemical Property:

Boiling Point:441.8oC at 760 mmHg
Flash Point:221oC
PSA：46.53000
Density:1.24g/cm3
LogP:3.81820
XLogP3:4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:290.0709720
Heavy Atom Count:20
Complexity:313

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)CC1=CC(=CC(=C1)O)C2=CC=C(C=C2)Cl

Technology Process of (1,1'-Biphenyl)-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester

There total 8 articles about (1,1'-Biphenyl)-3-acetic acid, 4'-chloro-5-hydroxy-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3160-40-5
4-(4-chlorophenyl)-3-buten-2-one

: 61888-75-3
4'-Chlor-5-hydroxy-3-biphenylylessigsaeure-ethylester

Guidance literature:: Multi-step reaction with 7 steps

1: (i) NaOMe, MeOH, (ii) aq. NaOH, (iii) aq. HCl

2: POCl₃, Na₂CO₃ / toluene

3: Na / toluene

4: Br₂ / benzene

5: aq. NaOH / methanol

6: aq. HBr, AcOH

7: H₂SO₄ / benzene

With sodium hydroxide; sulfuric acid; hydrogen bromide; bromine; sodium; sodium carbonate; acetic acid; trichlorophosphate; In methanol; toluene; benzene;
DOI:10.1021/jm00215a018

Reference yield:

: 27463-38-3
5-(4-chlorophenyl)cyclohexane-1,3-dione

: 61888-75-3
4'-Chlor-5-hydroxy-3-biphenylylessigsaeure-ethylester

Guidance literature:: Multi-step reaction with 6 steps

1: POCl₃, Na₂CO₃ / toluene

2: Na / toluene

3: Br₂ / benzene

4: aq. NaOH / methanol

5: aq. HBr, AcOH

6: H₂SO₄ / benzene

With sodium hydroxide; sulfuric acid; hydrogen bromide; bromine; sodium; sodium carbonate; acetic acid; trichlorophosphate; In methanol; toluene; benzene;
DOI:10.1021/jm00215a018

Reference yield:

: 53183-84-9
(4'-Chloro-5-methoxy-biphenyl-3-yl)-acetic acid methyl ester

: 61888-75-3
4'-Chlor-5-hydroxy-3-biphenylylessigsaeure-ethylester

Guidance literature:: Multi-step reaction with 3 steps

1: aq. NaOH / methanol

2: aq. HBr, AcOH

3: H₂SO₄ / benzene

With sodium hydroxide; sulfuric acid; hydrogen bromide; acetic acid; In methanol; benzene;
DOI:10.1021/jm00215a018