3-Biphenylacetic acid, 4'-chloro-5-methoxy-, methyl ester

Base Information

Chemical Name:3-Biphenylacetic acid, 4'-chloro-5-methoxy-, methyl ester
CAS No.:53183-84-9
Molecular Formula:C16H15ClO3
Molecular Weight:290.74
Hs Code.:2922299090
DSSTox Substance ID:DTXSID90201241
Nikkaji Number:J78.991G
Wikidata:Q83074422
ChEMBL ID:CHEMBL3244546
Mol file:53183-84-9.mol

Synonyms:BRN 2132188;53183-84-9;3-BIPHENYLACETIC ACID, 4'-CHLORO-5-METHOXY-, METHYL ESTER;4'-Chloro-5-methoxy-3-biphenylacetic acid methyl ester;CHEMBL3244546;DTXSID90201241;LS-44060;4'-Chloro-5-methoxy-1,1'-biphenyl-3-acetic acid methyl ester;[1,1'-Biphenyl]-3-acetic acid, 4'-chloro-5-methoxy-, methyl ester

Suppliers and Price of 3-Biphenylacetic acid, 4'-chloro-5-methoxy-, methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3-Biphenylacetic acid, 4'-chloro-5-methoxy-, methyl ester

Chemical Property:

Boiling Point:394.8°Cat760mmHg
Flash Point:151°C
PSA：35.53000
Density:1.194g/cm³
LogP:3.73110
XLogP3:3.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:290.0709720
Heavy Atom Count:20
Complexity:313

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1)C2=CC=C(C=C2)Cl)CC(=O)OC

Technology Process of 3-Biphenylacetic acid, 4'-chloro-5-methoxy-, methyl ester

There total 6 articles about 3-Biphenylacetic acid, 4'-chloro-5-methoxy-, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3160-40-5
4-(4-chlorophenyl)-3-buten-2-one

: 53183-84-9
(4'-Chloro-5-methoxy-biphenyl-3-yl)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: (i) NaOMe, MeOH, (ii) aq. NaOH, (iii) aq. HCl

2: POCl₃, Na₂CO₃ / toluene

3: Na / toluene

4: Br₂ / benzene

With bromine; sodium; sodium carbonate; trichlorophosphate; In toluene; benzene;
DOI:10.1021/jm00215a018

Reference yield:

: 27463-38-3
5-(4-chlorophenyl)cyclohexane-1,3-dione

: 53183-84-9
(4'-Chloro-5-methoxy-biphenyl-3-yl)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: POCl₃, Na₂CO₃ / toluene

2: Na / toluene

3: Br₂ / benzene

With bromine; sodium; sodium carbonate; trichlorophosphate; In toluene; benzene;
DOI:10.1021/jm00215a018

Reference yield:

: 54898-64-5
3-Chlor-5-(4-chlorphenyl)-2-cyclohexen-1-on

: 53183-84-9
(4'-Chloro-5-methoxy-biphenyl-3-yl)-acetic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: Na / toluene

2: Br₂ / benzene

With bromine; sodium; In toluene; benzene;
DOI:10.1021/jm00215a018