5-Acetyl-1-benzyl-4-phenyl-3,4-dihydro-1,5-benzodiazepin-2-one

Base Information

• Chemical Name: 5-Acetyl-1-benzyl-4-phenyl-3,4-dihydro-1,5-benzodiazepin-2-one
• CAS No.: 105931-88-2
• Molecular Formula: C24H22 N2 O2
• Molecular Weight: 0
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID50909832
• Mol file: 105931-88-2.mol

Synonyms:105931-88-2;BRN 4560496;5-acetyl-1-benzyl-4-phenyl-3,4-dihydro-1,5-benzodiazepin-2-one;5-acetyl-1-benzyl-4-phenyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepin-2-one;1,3,4,5-Tetrahydro-5-acetyl-4-phenyl-1-(phenylmethyl)-2H-1,5-benzodiazepin-2-one;2H-1,5-Benzodiazepin-2-one, 1,3,4,5-tetrahydro-5-acetyl-4-phenyl-1-(phenylmethyl)-;1,3,4,5-Tetrahydro-5-acetyl-4-phenyl-1-(phenylmethyl)-2H-1,5-benzodiaz epin-2-one;ChemDiv1_028003;Oprea1_733976;HMS666I19;DTXSID50909832;ZNNXJHMWQNPUBZ-UHFFFAOYSA-N;STK676299;AKOS005594198;LS-34332;EU-0052432;SR-01000528650;SR-01000528650-1

Chemical Property of 5-Acetyl-1-benzyl-4-phenyl-3,4-dihydro-1,5-benzodiazepin-2-one

Chemical Property:

• Vapor Pressure: 8.59E-18mmHg at 25°C
• Boiling Point: 669.6°Cat760mmHg
• Flash Point: 321.6°C
• PSA: 40.62000
• Density: 1.209g/cm³
• LogP: 4.84770
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 370.168127949
• Heavy Atom Count: 28
• Complexity: 551

Purity/Quality:

1,3,4,5-TETRAHYDRO-5-ACETYL-4-PHENYL-1-(PHENYLMETHYL)-2H-1,5-BENZODIAZ EPIN-2-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)N1C(CC(=O)N(C2=CC=CC=C21)CC3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 5-Acetyl-1-benzyl-4-phenyl-3,4-dihydro-1,5-benzodiazepin-2-one

There total 1 articles about 5-Acetyl-1-benzyl-4-phenyl-3,4-dihydro-1,5-benzodiazepin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

benzyl bromide (100-39-0) + 5-acetyl-4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one (16442-59-4) → 1-benzyl-4-phenyl-5-acetyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one (105931-88-2)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In benzene;

DOI:10.1007/BF00519945

upstream raw materials:

benzyl bromide

5-acetyl-4-phenyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one