Ethyl 5-methyl-4-nitrothiophene-2-carboxylate

Base Information

Chemical Name:Ethyl 5-methyl-4-nitrothiophene-2-carboxylate
CAS No.:66117-23-5
Molecular Formula:C8H9 N O4 S
Molecular Weight:215.2264
Hs Code.:
NSC Number:157789
DSSTox Substance ID:DTXSID00303301
Wikidata:Q82048493

Synonyms:66117-23-5;ethyl 5-methyl-4-nitrothiophene-2-carboxylate;NSC157789;SCHEMBL17977297;DTXSID00303301;NSC-157789

Suppliers and Price of Ethyl 5-methyl-4-nitrothiophene-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Ethyl 5-methyl-4-nitrothiophene-2-carboxylate

Chemical Property:

Vapor Pressure:9.23E-05mmHg at 25°C
Boiling Point:339.4°Cat760mmHg
Flash Point:159°C
Density:1.333g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:215.02522894
Heavy Atom Count:14
Complexity:240

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=C(S1)C)[N+](=O)[O-]

Technology Process of Ethyl 5-methyl-4-nitrothiophene-2-carboxylate

There total 7 articles about Ethyl 5-methyl-4-nitrothiophene-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 64-17-5
ethanol

: 36050-35-8
5-methyl-4-nitro-thiophene-2-carboxylic acid

: 66117-23-5
ethyl 5-methyl-4-nitrothiophene-2-carboxylate

Guidance literature:: With hydrogen cation; Heating;
DOI:10.1016/j.bmc.2003.11.003

Reference yield:

: 1918-79-2
2-methylthiophene-5-carboxylic acid

: 66117-23-5
ethyl 5-methyl-4-nitrothiophene-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: HNO₃; H₂SO₄ / 0 - 5 °C

2: H⁺ / Heating

With sulfuric acid; nitric acid; hydrogen cation;
DOI:10.1016/j.bmc.2003.11.003

Reference yield:

: 36050-35-8
5-methyl-4-nitro-thiophene-2-carboxylic acid

: 66117-23-5
ethyl 5-methyl-4-nitrothiophene-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride; benzene

With thionyl chloride; benzene;
DOI:10.1021/ja01152a073