1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-, hydrazone, monohydrochloride

Base Information

Chemical Name:1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-, hydrazone, monohydrochloride
CAS No.:65871-41-2
Molecular Formula:C9H11ClN4S
Molecular Weight:242.7284
Hs Code.:
DSSTox Substance ID:DTXSID70216050
ChEMBL ID:CHEMBL555819

Synonyms:5-(2-Methylphenyl)-1,3,4-thiadiazol-2(3H)-one hydrazone hydrochloride;1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-, hydrazone, monohydrochloride;65871-41-2;C9H10N4S.ClH;CHEMBL555819;SCHEMBL11561831;C9-H10-N4-S.Cl-H;DTXSID70216050;SLFBMDDKFCRYAX-UHFFFAOYSA-N;LS-150334;2-hydrazino-5-(2-methylphenyl)-1,3,4-thiadiazole hydrochloride

Suppliers and Price of 1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-, hydrazone, monohydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-, hydrazone, monohydrochloride

Chemical Property:

Vapor Pressure:2.9E-06mmHg at 25°C
Boiling Point:389.2°C at 760 mmHg
Flash Point:189.2°C
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:242.0392952
Heavy Atom Count:15
Complexity:190

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=CC=C1C2=NN=C(S2)NN.Cl

Technology Process of 1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-, hydrazone, monohydrochloride

There total 3 articles about 1,3,4-Thiadiazol-2(3H)-one, 5-(2-methylphenyl)-, hydrazone, monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 40642-55-5
2-chloro-5-(2-methylphenyl)-1,3,4-thiadiazole

: 65871-41-2
2-hydrazino-5-(2-methylphenyl)-1,3,4-thiadiazole hydrochloride

Guidance literature:: With hydrogenchloride; hydrazine hydrate; In ethanol; for 4h; Heating;
DOI:10.1021/jm00400a003

Reference yield:

: 118-90-1
ortho-methylbenzoic acid

: 65871-41-2
2-hydrazino-5-(2-methylphenyl)-1,3,4-thiadiazole hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1: polyphosphoric acid / 4 h / 80 - 90 °C

2: conc. HCl, aq. NaNO₂, copper, glacial acetic acid / 4 h / 15 - 20 °C

3: 47 percent / 1.) hydrazine hydrate, 2.) HCl / ethanol / 4 h / Heating

With hydrogenchloride; PPA; copper; hydrazine hydrate; acetic acid; sodium nitrite; In ethanol;
DOI:10.1021/jm00400a003

Reference yield:

: 59565-54-7
5-(2-methylphenyl)-1,3,4-thiadiazol-2-amine

: 65871-41-2
2-hydrazino-5-(2-methylphenyl)-1,3,4-thiadiazole hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1: conc. HCl, aq. NaNO₂, copper, glacial acetic acid / 4 h / 15 - 20 °C

2: 47 percent / 1.) hydrazine hydrate, 2.) HCl / ethanol / 4 h / Heating

With hydrogenchloride; copper; hydrazine hydrate; acetic acid; sodium nitrite; In ethanol;
DOI:10.1021/jm00400a003