Technology Process of Furegrelate
There total 5 articles about Furegrelate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanol; sodium hydroxide;
at 0 - 20 ℃;
for 1.5h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: pyridine / dichloromethane / 3 h / 0 - 20 °C / Inert atmosphere; Sealed tube
2: pyridine; 1,1'-bis-(diphenylphosphino)ferrocene; 1,10-Phenanthroline; Dimethyl oxalate; manganese; nickel(II) bromide 2-methoxyethyl ether complex; aluminum (III) chloride / N,N-dimethyl-formamide / 40 h / 100 °C / Inert atmosphere; Sealed tube
3: sodium hydroxide / methanol; water / 1.5 h / 20 °C / Inert atmosphere; Sealed tube
With
pyridine; Dimethyl oxalate; aluminum (III) chloride; 1,1'-bis-(diphenylphosphino)ferrocene; manganese; 1,10-Phenanthroline; nickel(II) bromide 2-methoxyethyl ether complex; sodium hydroxide;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1021/jacs.0c12462
- Guidance literature:
-
Multi-step reaction with 2 steps
1: pyridine; 1,1'-bis-(diphenylphosphino)ferrocene; 1,10-Phenanthroline; Dimethyl oxalate; manganese; nickel(II) bromide 2-methoxyethyl ether complex; aluminum (III) chloride / N,N-dimethyl-formamide / 40 h / 100 °C / Inert atmosphere; Sealed tube
2: sodium hydroxide / methanol; water / 1.5 h / 20 °C / Inert atmosphere; Sealed tube
With
pyridine; Dimethyl oxalate; aluminum (III) chloride; 1,1'-bis-(diphenylphosphino)ferrocene; manganese; 1,10-Phenanthroline; nickel(II) bromide 2-methoxyethyl ether complex; sodium hydroxide;
In
methanol; water; N,N-dimethyl-formamide;
DOI:10.1021/jacs.0c12462
