1646-28-2

Basic information

• Product Name: Methyl 5-hydroxybenzofuran-2-carboxylate
• Synonyms: Methyl 5-hydroxybenzofuran-2-carboxylate;2-BENZOFURANCARBOXYLIC ACID, 5-HYDROXY-, METHYL ESTER
• CAS NO: 1646-28-2
• Molecular Formula: C₁₀H₈O₄
• Molecular Weight: 192.16812
• Mol File: 1646-28-2.mol
• Article Data: 12

Chemical Properties

• Melting Point: 168-169 °C(Solv: methanol (67-56-1); water (7732-18-5))
• Boiling Point: 326.2±22.0 °C(Predicted)
• Appearance: /
• Density: 1.346±0.06 g/cm3(Predicted)
• PKA: 8.89±0.40(Predicted)
• CAS DataBase Reference: Methyl 5-hydroxybenzofuran-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: Methyl 5-hydroxybenzofuran-2-carboxylate(1646-28-2)
• EPA Substance Registry System: Methyl 5-hydroxybenzofuran-2-carboxylate(1646-28-2)

Safety Data

• Hazardous Substances Data: 1646-28-2(Hazardous Substances Data)

Upstream product

• 1751-24-2 5-methoxy-benzofuran-2-carboxylic acid methyl ester 
• 67-56-1 methanol 
• 10242-08-7 5-methoxybenzofuran-2-carboxylic acid 
• 50551-56-9 ethyl 5-methoxybenzofuran-2-carboxylate 
• 56172-36-2 5-Hydroxybenzofuran-2-carboxylic acid 
• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 54125-02-9 danishefsky's diene 
• 1874-23-3 methyl 5-nitrofuran-2-carboxylate 

Downstream Products

• 85666-24-6 Furegrelate 
• 1093631-45-8 5-[4-({[3-(2,6-dichlorophenyl)-5-(1-methylethyl)-4-isoxazolyl]methyl}oxy)phenyl]-1-benzofuran-2-carboxylic acid 
• 1093631-70-9 methyl 5-(4-hydroxyphenyl)-1-benzofuran-2-carboxylate 
• 155587-71-6 6-Amino-5-hydroxybenzofuran-2-carbonsaeure-methylester 
• 1027017-24-8 2-{cyclohexyl-[5-(quinolin-2-ylmethoxy)-benzofuran-2-yl]-methoxy}-isoindole-1,3-dione 
• 1026457-69-1 O-{cyclohexyl-[5-(quinolin-2-ylmethoxy)-benzofuran-2-yl]-methyl}-hydroxylamine 
• 1026925-87-0 cyclohexyl-[5-(quinolin-2-ylmethoxy)-benzofuran-2-yl]-methanol 

Relevant articles and documents

BITTER TASTE MODULATORS

The present invention includes antagonists of human type 2 taste receptors (hT2Rs) having structural Formula (I). The present invention also provides compositions containing these antagonists, the use of these antagonists for modulating taste perception, particularly bitter taste, and the method of preparing these antagonists (I).

FARNESOID X RECEPTOR AGONISTS

The present invention relates to famesoid X receptors (FXR, NR1 H4) FXR is a member of the nuclear receptor class of ligand-activated transcription factors More particularly, the present invention relates to compounds useful as agonists for FXR, pharmaceu