4-methyl-N-tritylbenzenesulfonamide

Base Information

• Chemical Name: 4-methyl-N-tritylbenzenesulfonamide
• CAS No.: 861-67-6
• Molecular Formula: C26H23NO2S
• Molecular Weight: 413.54
• Mol file: 861-67-6.mol

Synonyms:

Chemical Property of 4-methyl-N-tritylbenzenesulfonamide

Chemical Property:

• Vapor Pressure: 1.32E-13mmHg at 25°C
• Boiling Point: 583.5°C at 760 mmHg
• Flash Point: 306.7°C
• Density: 1.201g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-methyl-N-tritylbenzenesulfonamide

There total 10 articles about 4-methyl-N-tritylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

triphenylmethyl alcohol (76-84-6) + N-sulfinyl-p-toluenesulfonamide (4104-47-6) → N-(triphenylmethyl)-p-toluenesulfonamide (861-67-6)

Guidance literature:

In xylene; at 100 - 110 ℃; for 0.5h; Product distribution; Mechanism; further solvents, reaction times, and temperatures. Structure of products depends on the structure of alcohol (in case of tri- and diphenylmethanol and allylic alcohols products are viz N-substituted sulfonamides).;

DOI:10.1016/S0040-4020(01)92026-5

Reference yield: 86.0%

triphenylmethane (519-73-3) + bromamine T (41085-71-6) → N-(triphenylmethyl)-p-toluenesulfonamide (861-67-6)

Guidance literature:

With [Fe(N,N-bis(2-pyridyl-methyl)bis(2-pyridyl)methylamine)(CH₃CN)](ClO₄)2; In acetonitrile; for 4h;

DOI:10.1039/c4ra02240h

Reference yield: 74.0%

triphenylmethane (519-73-3) + [N-(p-tolylsulfonyl)imino]phenyliodinane (55962-05-5) → Triphenylmethylamin (5824-40-8) + N-(triphenylmethyl)-p-toluenesulfonamide (861-67-6)

Guidance literature:

With [CuI(tris[(tetramethylguanidino)-phenyl]amine)][PF₆]; In nitromethane; for 12h; Inert atmosphere; Molecular sieve;

DOI:10.1021/ja503869j

upstream raw materials:

Triphenylmethylamin

triphenylmethyl alcohol

N-sulfinyl-p-toluenesulfonamide

Tosyl isocyanate

Refernces

• 1、 Wang, Haiyu,Li, Yuxi,Wang, Zhiming,Lou, Jun,Xiao, Yuling,Qiu, Guofu,Hu, Xianming,Altenbach, Hans-Josef,Liu, Peng. "Iron-catalyzed efficient intermolecular amination of C(sp3)-H bonds with bromamine-T as nitrene source". . p. 25287 - 25290. Retrieved 2014/07/07.
• 2、 Barman, Dipti N.,Nicholas, Kenneth M.. "Ligand-assisted, copper-catalyzed enantioselective benzylic amination". supporting information; experimental part. p. 1815 - 1818. Retrieved 2010/09/07.