2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96

Base Information

Chemical Name:2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96
CAS No.:41530-32-9
Molecular Formula:C9H12 O5
Molecular Weight:200.191
Hs Code.:2918990090
Mol file:41530-32-9.mol

Synonyms:Propanedioicacid, (3-methoxy-2-propenylidene)-, dimethyl ester (9CI); Dimethyl 3-methoxyallylidenemalonate

Suppliers and Price of 2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Dimethyl3-Methoxyallylidenemalonate
25g
$ 265.00

Crysdot
Dimethyl2-(3-methoxyallylidene)malonate 95+%
100g
$ 872.00

Atlantic Research Chemicals
Dimethyl[(2E)-3-Methoxyprop-2-enylidene]malonate 95%
5gm:
$ 84.83

American Custom Chemicals Corporation
2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER 95.00%
5MG
$ 502.80

Total 14 raw suppliers

Chemical Property of 2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96

Chemical Property:

Vapor Pressure:0.0169mmHg at 25°C
Refractive Index:1.5380 (estimate)
Boiling Point:254.8°Cat760mmHg
Flash Point:105.9°C
PSA：61.83000
Density:1.128g/cm³
LogP:0.41890

Purity/Quality:

99%, ^*data from raw suppliers

Dimethyl3-Methoxyallylidenemalonate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses Dimethyl 3-Methoxyallylidenemalonate is used to prepare pyridinonyl PDK1 inhibitors and pyrrolo[3,2-c]pyridine derivatives as kinase inhibitors for treating cancer.

Technology Process of 2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96

There total 2 articles about 2-(3-METHOXYALLYLIDENE)MALONIC ACID DIMETHYL ESTER, 96 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 102-52-3
malonaldehydebis(dimethylacetal)

: 108-59-8
malonic acid dimethyl ester

: 41530-32-9
1,3-dimethyl 2-(3-methoxyprop-2-en-1-ylidene)propanedioate

Guidance literature:: With acetic anhydride; zinc(II) chloride; at 140 ℃; for 1h;

Reference yield:

: 41530-32-9
1,3-dimethyl 2-(3-methoxyprop-2-en-1-ylidene)propanedioate

Guidance literature:: 1,1,3,3-Tetramethoxypropan, Malonsaeuredimethylester;

Reference yield: 90.0%

: 41530-32-9
1,3-dimethyl 2-(3-methoxyprop-2-en-1-ylidene)propanedioate

: 72235-53-1
3,4-difluorobenzylamine

: 1001413-01-9
1-(3,4-difluoro-benzyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid

Guidance literature:: 1,3-dimethyl 2-(3-methoxyprop-2-en-1-ylidene)propanedioate; 3,4-difluorobenzylamine; In iso-butanol; at 5 - 100 ℃;

With water; sodium hydroxide; In methanol; iso-butanol; at 20 ℃; for 2h;

With hydrogenchloride; In methanol; water; iso-butanol;