Iodopride

Base Information

Chemical Name:Iodopride
CAS No.:115860-70-3
Molecular Formula:C15H21 I N2 O2
Molecular Weight:388.24
Hs Code.:
DSSTox Substance ID:DTXSID40151207
Wikidata:Q83017609
ChEMBL ID:CHEMBL2115023
Mol file:115860-70-3.mol

Synonyms:iodopride;iodopride 125I hydrochloride, (S)-isomer;iodopride HCl, (R)-isomer;iodopride hydrochloride, (S)-isomer;iodopride, (S)-isomer;N-((1-ethyl-2-pyrrolidinyl)methyl)-5-iodo-2-methoxybenzamide

Suppliers and Price of Iodopride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of Iodopride

Chemical Property:

Vapor Pressure:3.66E-08mmHg at 25°C
Boiling Point:446.4°Cat760mmHg
Flash Point:223.8°C
PSA：45.06000
Density:1.442g/cm³
LogP:3.02660
XLogP3:2.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:388.06478
Heavy Atom Count:20
Complexity:327

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1CCCC1CNC(=O)C2=C(C=CC(=C2)I)OC
Isomeric SMILES:CCN1CCC[C@@H]1CNC(=O)C2=C(C=CC(=C2)I)OC

Technology Process of Iodopride

There total 3 articles about Iodopride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 22795-97-7
(R)-2-aminomethyl-1-ethylpyrrolidine

: 115860-69-0
2-methoxy-5-iodobenzoyl chloride

: 115860-70-3
(R)-N-<(1-ethyl-2-pyrrolidinyl)methyl>-5-iodo-2-methoxybenzamide

Guidance literature:: In dichloromethane; for 0.583333h;
DOI:10.1021/jm00118a031

Reference yield:

: di-L-(+)-tartrate salt of (R)-2-aminomethyl-2-ethyl-pyrrolidine

: bis-hydrochloride mono-hydrate

: 2786-00-7
2-methoxy-5-iodobenzoic acid

: 115860-69-0
2-methoxy-5-iodobenzoyl chloride

: iodobenzamide hydrochloride hydrate

: 115860-70-3
(R)-N-<(1-ethyl-2-pyrrolidinyl)methyl>-5-iodo-2-methoxybenzamide

Guidance literature:: With hydrogenchloride; In sodium hydroxide; dichloromethane; water; acetone;

Reference yield:

: 2786-00-7
2-methoxy-5-iodobenzoic acid

: 115860-70-3
(R)-N-<(1-ethyl-2-pyrrolidinyl)methyl>-5-iodo-2-methoxybenzamide

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / CH₂Cl₂ / 30 °C

2: 81 percent / CH₂Cl₂ / 0.58 h

With thionyl chloride; In dichloromethane;
DOI:10.1021/jm00118a031