trans-3-Hydroxy-6-methoxy-1-methyl-3,6-bis(phenylmethyl)-2,5-piperazinedione

Base Information

Chemical Name:trans-3-Hydroxy-6-methoxy-1-methyl-3,6-bis(phenylmethyl)-2,5-piperazinedione
CAS No.:87291-18-7
Molecular Formula:C₂₀H₂₂N₂O₄
Molecular Weight:354.406
Hs Code.:
Mol file:87291-18-7.mol

Synonyms:

Suppliers and Price of trans-3-Hydroxy-6-methoxy-1-methyl-3,6-bis(phenylmethyl)-2,5-piperazinedione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of trans-3-Hydroxy-6-methoxy-1-methyl-3,6-bis(phenylmethyl)-2,5-piperazinedione

Chemical Property:

PSA：78.87000
LogP:1.35800

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of trans-3-Hydroxy-6-methoxy-1-methyl-3,6-bis(phenylmethyl)-2,5-piperazinedione

There total 6 articles about trans-3-Hydroxy-6-methoxy-1-methyl-3,6-bis(phenylmethyl)-2,5-piperazinedione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 109619-77-4
3,6-di(α-bromobenzyl)-3-hydroxy-6-methoxy-1-methyl-2,5-piperazinedione

: 87291-18-7,109715-79-9,109715-80-2
picrorocellin

Guidance literature:: With hydrogen; triethylamine; palladium on activated charcoal; In ethyl acetate; for 0.5h; Ambient temperature;
DOI:10.1246/cl.1986.1453

Reference yield:

: 100-52-7
benzaldehyde

: 87291-18-7,109715-79-9,109715-80-2
picrorocellin

Guidance literature:: Multi-step reaction with 6 steps

1: t-BuOK

3: 98 percent / t-BuOK

4: 95 percent / water, N-bromosuccinimide

5: 70 percent / N-bromosuccinimide / CHCl₃ / 3 h / Ambient temperature

6: 60 percent / H₂, triethylamine / 10 percent Pd/C / ethyl acetate / 0.5 h / Ambient temperature

With N-Bromosuccinimide; potassium tert-butylate; water; hydrogen; triethylamine; palladium on activated charcoal; In chloroform; ethyl acetate;
DOI:10.1246/cl.1986.1453

Reference yield:

: 80687-66-7
(Z)-1-acetyl-3-benzylidene-4-methylpiperazine-2,5-dione

: 87291-18-7,109715-79-9,109715-80-2
picrorocellin

Guidance literature:: Multi-step reaction with 4 steps

1: 98 percent / t-BuOK

2: 95 percent / water, N-bromosuccinimide

3: 70 percent / N-bromosuccinimide / CHCl₃ / 3 h / Ambient temperature

4: 60 percent / H₂, triethylamine / 10 percent Pd/C / ethyl acetate / 0.5 h / Ambient temperature

With N-Bromosuccinimide; potassium tert-butylate; water; hydrogen; triethylamine; palladium on activated charcoal; In chloroform; ethyl acetate;
DOI:10.1246/cl.1986.1453