4-(4-Chlorostyryl)pyridine

Base Information

Chemical Name:4-(4-Chlorostyryl)pyridine
CAS No.:2502-99-0
Molecular Formula:C₁₃H₁₀ClN
Molecular Weight:215.682
Hs Code.:
European Community (EC) Number:636-720-2
NSC Number:364046
Nikkaji Number:J3.060.921B,J303.415A
Mol file:2502-99-0.mol

Synonyms:4-(4-Chlorostyryl)pyridine;46459-15-8;(E)-4-(4-chlorostyryl)pyridine;SCHEMBL9332785;NSC364046;AKOS002375985;NSC-364046;F13644;F3099-6975

Suppliers and Price of 4-(4-Chlorostyryl)pyridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-[(1Z)-2-(4-Chlorophenyl)vinyl]pyridine
25mg
$ 220.00

American Custom Chemicals Corporation
4-(4-CHLOROSTYRYL)PYRIDINE 95.00%
5MG
$ 499.69

Total 6 raw suppliers

Chemical Property of 4-(4-Chlorostyryl)pyridine

Chemical Property:

Vapor Pressure:0.000114mmHg at 25°C
Melting Point:110 °C
Boiling Point:346.7°C at 760 mmHg
PKA:5.63±0.10(Predicted)
Flash Point:194.3°C
PSA：12.89000
Density:1.212g/cm³
LogP:3.90540
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:215.0501770
Heavy Atom Count:15
Complexity:201

Purity/Quality:

99% ^*data from raw suppliers

4-[(1Z)-2-(4-Chlorophenyl)vinyl]pyridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C=CC2=CC=NC=C2)Cl
Isomeric SMILES:C1=CC(=CC=C1/C=C/C2=CC=NC=C2)Cl

Technology Process of 4-(4-Chlorostyryl)pyridine

There total 3 articles about 4-(4-Chlorostyryl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 100-43-6,329041-72-7
4-vinylpyridine

: 1679-18-1
4-Chlorophenylboronic acid

: 2502-99-0,5847-63-2,46459-15-8,102045-66-9
(E)-4-(4-chlorostyryl)pyridine

Guidance literature:: With palladium(II) acetylacetonate; oxygen; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 90 ℃; for 24h; under 760.051 Torr;
DOI:10.3184/174751912X13352864811920

Reference yield:

: 872-85-5
pyridine-4-carbaldehyde

: 39225-17-7
diethyl 4-chlorobenzylphosphonate

: 2502-99-0,5847-63-2,46459-15-8,102045-66-9
(E)-4-(4-chlorostyryl)pyridine

Guidance literature:: With potassium tert-butylate; In tert-butyl alcohol; at -15 ℃;
DOI:10.1039/c2cc15453f

Reference yield:

: 104-83-6
1-Chloro-4-(chloromethyl)benzene

: 2502-99-0,5847-63-2,46459-15-8,102045-66-9
(E)-4-(4-chlorostyryl)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: tetrahydrofuran / 4 h / Reflux

2: sodium hydride / tetrahydrofuran / 1 h / Cooling with ice; Reflux

With sodium hydride; In tetrahydrofuran;
DOI:10.1002/poc.4246